テンプレート:PBB/1270のソースを表示

{{GNF_Protein_box
 | Name = Ciliary neurotrophic factor
 | image = Protein_CNTF_PDB_1cnt.png
 | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1cnt.
 | PDB = {{PDB2|1CNT}}
 | HGNCid = 2169
 | MGIid = 88439
 | Symbol = CNTF
 | AltSymbols =; HCNTF
 | IUPHAR = 
 | OMIM = 118945
 | ECnumber = 
 | Homologene = 8288
 | GeneAtlas_image1 = PBB_GE_CNTF_208597_at_tn.png
 | GeneAtlas_image2 = 
 | GeneAtlas_image3 = 
 | Protein_domain_image = 
 | Function = {{GNF_GO|id=GO:0005125 |text = cytokine activity}} {{GNF_GO|id=GO:0005127 |text = ciliary neurotrophic factor receptor binding}} {{GNF_GO|id=GO:0005138 |text = interleukin-6 receptor binding}} {{GNF_GO|id=GO:0008083 |text = growth factor activity}}
 | Component = {{GNF_GO|id=GO:0005615 |text = extracellular space}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005829 |text = cytosol}} {{GNF_GO|id=GO:0030424 |text = axon}} {{GNF_GO|id=GO:0032838 |text = cell projection cytoplasm}} {{GNF_GO|id=GO:0043025 |text = neuronal cell body}} {{GNF_GO|id=GO:0043231 |text = intracellular membrane-bounded organelle}}
 | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0008284 |text = positive regulation of cell proliferation}} {{GNF_GO|id=GO:0014068 |text = positive regulation of phosphatidylinositol 3-kinase cascade}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}} {{GNF_GO|id=GO:0030307 |text = positive regulation of cell growth}} {{GNF_GO|id=GO:0040007 |text = growth}} {{GNF_GO|id=GO:0042517 |text = positive regulation of tyrosine phosphorylation of Stat3 protein}} {{GNF_GO|id=GO:0043410 |text = positive regulation of MAPK cascade}} {{GNF_GO|id=GO:0043524 |text = negative regulation of neuron apoptosis}} {{GNF_GO|id=GO:0043526 |text = neuroprotection}} {{GNF_GO|id=GO:0046427 |text = positive regulation of JAK-STAT cascade}} {{GNF_GO|id=GO:0046533 |text = negative regulation of photoreceptor cell differentiation}} {{GNF_GO|id=GO:0046668 |text = regulation of retinal cell programmed cell death}} {{GNF_GO|id=GO:0046887 |text = positive regulation of hormone secretion}} {{GNF_GO|id=GO:0048143 |text = astrocyte activation}} {{GNF_GO|id=GO:0048644 |text = muscle organ morphogenesis}} {{GNF_GO|id=GO:0048666 |text = neuron development}} {{GNF_GO|id=GO:0048680 |text = positive regulation of axon regeneration}} {{GNF_GO|id=GO:0060075 |text = regulation of resting membrane potential}} {{GNF_GO|id=GO:0060081 |text = membrane hyperpolarization}} {{GNF_GO|id=GO:0070120 |text = ciliary neurotrophic factor-mediated signaling pathway}}
 | Hs_EntrezGene = 1270
 | Hs_Ensembl = ENSG00000242689
 | Hs_RefseqmRNA = NM_000614.3
 | Hs_RefseqProtein = NP_000605.1
 | Hs_GenLoc_db = hg19
 | Hs_GenLoc_chr = 11
 | Hs_GenLoc_start = 58390146
 | Hs_GenLoc_end = 58393198
 | Hs_Uniprot = P26441
 | Mm_EntrezGene = 12803
 | Mm_Ensembl = ENSMUSG00000079415
 | Mm_RefseqmRNA = NM_053007.2
 | Mm_RefseqProtein = NP_740756.1
 | Mm_GenLoc_db = mm9
 | Mm_GenLoc_chr = 19
 | Mm_GenLoc_start = 12838150
 | Mm_GenLoc_end = 12840122
 | Mm_Uniprot = P51642
 | path = PBB/1270
}}