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2013年10月6日 (日) 15:09時点における版

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|+ 表1．
|+ 表1．
|-
|-
| Classification||Target ||Year||Probe design ||References
| 分類||対象||年||プローブデザイン||参考文献
|-
|-
| Small molecule || カルシウム || 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref>
|rowspan="21" | 生体内小分子|| [[カルシウム]] || 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref>
|-
|-
| Small molecule || サイクリックGMP (cGMP) || 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref>  
|[[サイクリックGMP]] ([[cGMP]]) || 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref>  
|-
|-
| Small molecule || サイクリックAMP (cAMP) || 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>  
|[[サイクリックAMP]] ([[cAMP]]) || 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>  
|-
|-
| Small molecule || イノシトール3リン酸 (IP3) || 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>  
|[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) || 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>  
|-
|-
| Small molecule || 一酸化窒素 (NO) || 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
|[[一酸化窒素]] ([[NO]]) || 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
|-
|-
| Small molecule || アデノシン3リン酸 (ATP) || 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
|[[アデノシン3リン酸]] ([[ATP]]) || 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
|-
|-
| Small molecule || エストロゲン || 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref>
|[[エストロゲン]] || 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref>
|-
|-
| Small molecule || アンドロゲン || 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref>
|[[アンドロゲン]] || 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref>
|-
|-
| Small molecule || グルココルチコイド受容体リガンド || 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref>
|[[グルココルチコイド受容体]]リガンド || 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref>
|-
|-
| Small molecule || 神経成長因子 || 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
|[[神経成長因子]] || 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
|-
|-
| Small molecule || 核内受容体 || 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
|[[核内受容体]] || 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
|-
|-
| Small molecule || O-N-アセチルグルコサミン (O-GlcNAc) || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref>
|[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref>
|-
|-
| Small molecule || ビタミンA (レチノイン酸) || 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref>
|[[ビタミンA]] ([[レチノイン酸]]) || 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref>
|-
|-
| Small molecule || モリブデン酸 || 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref>
|[[wj:モリブデン酸|モリブデン酸]] || 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref>
|-
|-
| Small molecule || グルタミン酸 || 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref>
|[[グルタミン酸]] || 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref>
|-
|-
| Small molecule || Zn<sup>2+</sup> || 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
|[[wj:亜鉛|Zn<sup>2+</sup>]] || 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
|-
|-
| Small molecule || Cl<sup>-</sup> || 2000 || other || <ref><pubmed>11055428</pubmed></ref>
|[[wj:塩素|Cl<sup>-</sup>]] || 2000 || other || <ref><pubmed>11055428</pubmed></ref>
|-
|-
| Small molecule || 水素イオン濃度 (pH) || 2001 || other || <ref><pubmed>11716495</pubmed></ref>
|[[wj:水素イオン濃度|水素イオン濃度]] (pH) || 2001 || other || <ref><pubmed>11716495</pubmed></ref>
|-
|-
| Small molecule || グルコース || 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref>
|[[wj:グルコース|グルコース]] || 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref>
|-
|-
| Small molecule || Maltose || 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref>
|[[wj:マルトース|マルトース]]|| 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref>
|-
|-
| Small molecule || Ribose || 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref>
|[[wj:リボース|リボース]]|| 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref>
|-
|-
| Kinase || Calcium/Calmodulin-dependent protein kinase II (CaMKII) || 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref>
| Kinase || [[カルシウム/カルモジュリン依存製タンパク質キナーゼII]] ([[CaMKII]]) || 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref>
|-
|-
| Kinase || Src || 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref>
| Kinase || [[Src]] || 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref>
|-
|-
| Kinase || Protein kinase C (PKC) || 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref>
| Kinase || Protein kinase C (PKC) || 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref>
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| Kinase || Protein kinase D (PKD) || 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref>
| Kinase || Protein kinase D (PKD) || 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref>
|-
|-
| Kinase || Protein kinase A (PKA) || 2000, 2001 || 3-3 || <ref><pubmed>10700148, 11752448</pubmed></ref>
| Kinase || Protein kinase A (PKA) || 2000, 2001 || 3-3 || <ref><pubmed>10700148</pubmed></ref><ref><pubmed>11752448</pubmed></ref>
|- Table 1 A list of genetically encoded FRET probes.
|- Table 1 A list of genetically encoded FRET probes.
| Kinase || Abl || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
| Kinase || Abl || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
|-
|-
| Kinase || Bcr-Abl || 2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref>
| Kinase || Bcr-Abl || 2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref>
|- The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.
|-
| Kinase || c-Raf || 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref>
| Kinase || c-Raf || 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref>
|-
|-
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| Kinase || Myosine light chain kinase || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
| Kinase || Myosine light chain kinase || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
|-
|-
| Kinase || JNK || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref><pubmed> 21976697</pubmed></ref>
| Kinase || JNK || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref>
|-
|-
| Kinase || RSK || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref>
| Kinase || RSK || 2011 || 3-3 || <ref name=ref21976697></ref>
|-
|-
| Kinase || S6K || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref>
| Kinase || S6K || 2011 || 3-3 || <ref name=ref21976697></ref>
|-
|-
| Kinase || Focal Adhesion Kinase (FAK) || 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
| Kinase || Focal Adhesion Kinase (FAK) || 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
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| Phosphatase || Calcineurin || 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref>
| Phosphatase || Calcineurin || 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref>
|-
|-
| Small GTPase || Ras || 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref><pubmed> 11429608</pubmed></ref>
| Small GTPase || Ras || 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref>
|-
|-
| Small GTPase || Rap || 2001 || 3-2 || <ref><pubmed>11429608</pubmed></ref>
| Small GTPase || Rap || 2001 || 3-2 || <ref name=ref11429608></ref>
|-
|-
| Small GTPase || Rac || 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref>
| Small GTPase || Rac || 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref>
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| Signal transduction || N-WASP || 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
| Signal transduction || N-WASP || 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
|-
|-
| Signal transduction || Adrenergic receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref>
| Signal transduction || Adrenergic receptor || 2003 || 3-1 || <ref name=ref12808462><pubmed>12808462</pubmed></ref>
|-
|-
| Signal transduction || Parathyroid hormone receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref>
| Signal transduction || Parathyroid hormone receptor || 2003 || 3-1 || <ref name=ref12808462></ref>
|-
|-
| Signal transduction || Plasma membrane Calcium pump || 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
| Signal transduction || Plasma membrane Calcium pump || 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
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| Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) || 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref>
| Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) || 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref>
|-
|-
| Lipid || Phosphatidylinositol (4,5)-bisphosphate (PIP2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
| Lipid || Phosphatidylinositol (4,5)-bisphosphate (PIP2) || 2008 || 3-4 || <ref name=ref18685081><pubmed>18685081</pubmed></ref>
|-
|-
| Lipid || Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
| Lipid || Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) || 2008 || 3-4 || <ref name=ref18685081></ref>
|-
|-
| Lipid || Phosphatidylinositol 4-phosphate (PI4P) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
| Lipid || Phosphatidylinositol 4-phosphate (PI4P) || 2008 || 3-4 || <ref name=ref18685081></ref>
|-
|-
| Lipid || Phosphatidic acid || 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref>
| Lipid || Phosphatidic acid || 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref>
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|-
|-
| Other || Redox || 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
| Other || Redox || 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
|-
|}
}
 
The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.


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