「Test」の版間の差分

提供：脳科学辞典
ナビゲーションに移動 検索に移動
細編集の要約なし
細 (内容を「<youtube>t7qizA4U9Ls</youtube>」で置換)
1行目: 1行目:
{| class="wikitable"
<youtube>t7qizA4U9Ls</youtube>
|+ 表1．
|-
| 分類||対象||プローブ名||年||プローブデザイン||参考文献
|-
|rowspan="21" | 生体内小分子|| [[カルシウム]] ||Cameleon|| 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref>
|-
|[[サイクリックGMP]] ([[cGMP]]) ||CGY, Cygnet, pGES-DE2, cGi|| 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref><ref><pubmed>23801067</pubmed></ref> 
|-
|[[サイクリックAMP]] ([[cAMP]]) ||Epac|| 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>
|-
|[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) ||LIBRA, Fretino, FIRE|| 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>
|-
|[[一酸化窒素]] ([[NO]]) ||NOA-1, Piccell|| 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
|-
|[[アデノシン3リン酸]] ([[ATP]]) ||A Team 1.03-nD/nA|| 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
|-
|[[エストロゲン]] ||SCCoR|| 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref>
|-
|[[アンドロゲン]] ||Ficaro|| 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref>
|-
|[[グルココルチコイド受容体]]リガンド ||GLUCOCOR|| 2007 || 3-3 || <ref><pubmed>15163683</pubmed></ref><ref><pubmed>17897691</pubmed></ref>
|-
|[[神経成長因子]] ||ECaus|| 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
|-
|[[核内受容体]] ||conpro|| 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
|-
|[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref>
|-
|[[ビタミンA]] ([[レチノイン酸]]) ||GEPRAS|| 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref>
|-
|[[wj:モリブデン酸|モリブデン酸]] ||MolyProbe|| 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref>
|-
|[[グルタミン酸]] ||FLIPE|| 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref>
|-
|[[wj:亜鉛|Zn<sup>2+</sup>]] ||eCALWY-1|| 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
|-
|[[wj:塩素|Cl<sup>-</sup>]] ||Clomeleon|| 2000 || other || <ref><pubmed>11055428</pubmed></ref>
|-
|[[wj:水素イオン濃度|水素イオン濃度]] (pH) ||GFpH, YFpH|| 2001 || other || <ref><pubmed>11716495</pubmed></ref>
|-
|[[wj:グルコース|グルコース]] ||FLIPglu|| 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref>
|-
|[[wj:マルトース|マルトース]]||FLIPmal|| 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref>
|-
|[[wj:リボース|リボース]]||FLIPrib|| 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref>
|-
|rowspan="25" | タンパク質リン酸化酵素 || [[カルシウム/カルモジュリン依存性タンパク質リン酸化酵素II]] ([[CaMKII]]) ||Camui α, green-Camui α, Camk2a reporter|| 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref name=ref23602566><pubmed> 23602566</pubmed></ref><ref name=ref21506563><pubmed> 21506563</pubmed></ref>
|-
| [[Src]] ||Srcus|| 2005, 2005, 2007 || 3-3 || <ref name=ref11752449><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref>
|-
| [[Ca2+／リン脂質依存性タンパク質リン酸化酵素|Ca<sup>2+</sup>／リン脂質依存性タンパク質リン酸化酵素]] ([[Cキナーゼ]], [[プロテインキナーゼC]], [[PKC]]) ||CKAR, CY-PKCdelta|| 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref>
|-
| [[タンパク質リン酸化酵素D]] ([[Dキナーゼ]], [[プロテインキナーゼD]], [[PKD]]) ||DKAR|| 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref>
|-
| [[cAMP依存性タンパク質リン酸化酵素]] ([[Aキナーゼ]], [[プロテインキナーゼA]], [[PKA]]) ||ART, AKAR|| 2000, 2001 || 3-3 || <ref><pubmed>10700148</pubmed></ref><ref><pubmed>11752448</pubmed></ref>
|-
| [[Abl]] ||Picchu|| 2001 || 3-3 || <ref name=ref11752449 />
|-
| [[Bcr]]-Abl ||Bcr-Abl activity sensor||2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref>
|-
| [[c-Raf]] ||Prin-cRaf|| 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref>
|-
| [[P21 protein-activated kinase 1]] ([[PAK1]]) ||Pakabi|| 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref>
|-
| [[B-raf]] ||Prin-Braf|| 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref>
|-
| [[Zeta-chain-associated protein kinase 70]] ([[ZAP-70]]) ||ROZA|| 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref>
|-
| [[Akt]] ||Aktus, BKAR, Akind|| 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref name=ref17407381><pubmed> 17407381</pubmed></ref>
|-
| [[細胞外シグナル調節キナーゼ]] ([[Extracellular signal-regulated kinases]], [[ERK]]) ||Miu2, Erkus, EKAR|| 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref>
|-
| [[インシュリン受容体]] ||Phocus|| 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref>
|-
| [[上皮成長因子受容体]] ([[EGFR]]) || ||2001 || 3-3 || <ref name=ref11752449 />
|-
| [[Ataxia telangiectasia mutated]] ([[ATM]]) || || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref>
|-
|[[オーロラBキナーゼ]] || || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref>
|-
| [[サイクリンB1]]-[[サイクリン依存性キナーゼ1]] || || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref>
|-
| [[ミオシン軽鎖キナーゼ]] ||MLCK-FIP || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
|-
| [[c-Jun N端末キナーゼ]] ([[JNK]]) ||JNKAR1, JUNKAR1EV || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref>
|-
| [[リボソームS6キナーゼ]] ([[RSK]], [[S6K]]) ||Eevee-RSK, Eevee-S6K|| 2011 || 3-3 || <ref name=ref21976697></ref>
|-
| [[接着斑キナーゼ]] ([[Focal Adhesion Kinase]], [[FAK]]) ||CYFAK413, FERM-sensor|| 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
|-
| [[Polo様キナーゼ1]] ([[polo-like kinase1]], [[PLK1]]) || || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref>
|-
| [[ストレス活性化プロテインキナーゼ3]] ([[Stress-Activated Protein Kinase Kinase Kinase]], [[stress-activated protein kinase 3]], [[SAP3K]]) || || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref>
|-
| [[細胞死関連タンパク質キナーゼ]] ([[death associated protein kinase 1]], [[DAPK1]]) ||DAPK1(334)-F40|| 2011 || 3-1 || <ref name=ref21506563 />
|-
| [[ホスファターゼ]] || [[カルシニューリン]] ||CaNAR1|| 2008, 2013 || 3-1 || <ref name=ref23602566 /><ref><pubmed> 18493642</pubmed></ref>
|-
|rowspan="8" | [[低分子量Gタンパク質]] || [[Ras]] ||Raichu-Ras, Fras|| 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref>
|-
| [[Rap]] ||Raichu-Rap|| 2001 || 3-2 || <ref name=ref11429608></ref>
|-
| [[Rac]] ||Raichu-Rac1|| 2004 || 3-2 || <ref name=ref14570905><pubmed>14570905</pubmed></ref>
|-
| [[Rab5]] ||Raichu-Rab5|| 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref>
|-
| [[Rho]] ||Raichu-RhoA|| 2003, 2011 || 3-2, 2 || <ref name=ref21423166><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref>
|-
| [[Cdc42]] ||Raichu-cdc42|| 2004, 2011 || 3-2, 2 || <ref name=ref14570905 /><ref name=ref21423166 />
|-
| [[Ral]] ||Raichu-Ral|| 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref>
|-
| [[TC10]] ||Raichu-TC10|| 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref>
|-
|rowspan="6" | [[シグナル伝達]] || [[RCC1]] ([[Ran]]に対する[[GDP, GTP交換因子]]) ||CFP-RCC1-YFP|| 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref>
|-
| [[CrkII]][[リン酸化]] ||Picchu|| 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref>
|-
| [[Wiskott-Aldrich syndrome-like]] ([[WASL]], [[neuronal Wiskott–Aldrich syndrome protein]], [[N-WASP]]) ||Stinger|| 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
|-
| [[アドレナリン受容体]] ||α<sub>2A</sub>AR-cam|| 2003 || 3-1 || <ref name=ref12808462><pubmed>12808462</pubmed></ref>
|-
| [[副甲状腺ホルモン受容体]] ||PTHR-cam|| 2003 || 3-1 || <ref name=ref12808462 />
|-
| [[細胞膜]][[カルシウムポンプ]] ||BFP-PMCA-GFP|| 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
|-
| [[アセチル化]] || ヒストンアセチル化 ||Histac|| 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref>
|-
|rowspan="6" | [[脂質]] || [[ホスファチジルイノシトール-3,4,5-三リン酸]] ([[PIP3|PIP<sub>3</sub>]]) ||Fllip, FLIMPA|| 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref>
|-
| [[ホスファチジルイノシトール-4,5-二リン酸]] ([[PIP2|PI(4,5)P<sub>2</sub>]]) ||Pippi-PI(4,5)P<sub>2</sub>|| 2008 || 3-4 || <ref name=ref18685081><pubmed>18685081</pubmed></ref>
|-
| [[ホスファチジルイノシトール-3,4-二リン酸]] ([[PI(3,4)P2|PI(3,4)P<sub>2</sub>]]) ||Pippi-PI(3,4)P<sub>2</sub>|| 2008 || 3-4 || <ref name=ref18685081 />
|-
| [[ホスファチジルイノシトール-4-リン酸]] ([[PI4P|PI4P]]) ||Pippi-PI(4)P|| 2008 || 3-4 || <ref name=ref18685081 />
|-
| [[ホスファチジン酸]] ||Pii|| 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref>
|-
| [[ジアシルグリセロール]] (DAG) ||Daglas, DIGDA|| 2006, 2008 || 3-4 || <ref name=ref18685081 /><ref><pubmed> 16990811</pubmed></ref>
|-
|rowspan="6" | タンパク質相互作用 || [[アクチン]] || ||2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref>
|-
| [[3-ホスホイノシチド依存性プロテインキナーゼ1]]（[[phosphoinositide-dependent protein kinase 1]], [[PDK1]])-[[タンパク質キナーゼB]] ([[protein kinase B]], [[PKB]], [[Akt]])相互作用 || ||2007 || 2 || <ref name=ref17407381 />
|-
| [[蛋白質チロシン脱リン酸化酵素1B]] ([[protein tyrosine phosphatase 1B]], [[PTP 1B]])-[[受容体型チロシンキナーゼ]] ([[receptor tyrosine kinase]]s, [[RTK]]s)相互作用 || || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref>
|-
| [[乳癌耐性タンパク質]] ([[breast cancer resistance protein]], [[BCRP]])/[[ATP結合カセット輸送体]] ([[ATP-binding cassette sub-family G member]], [[ABCG]])相互作用 || ||2010 || 2 || <ref><pubmed>20622991</pubmed></ref>
|-
| [[コフィリン]]-[[アクチン]]相互作用 || ||2008 || 2 || <ref><pubmed>17993279</pubmed></ref>
|-
| [[第10染色体ホスファターゼ・テンシン・ホモログ]] ([[Phosphatase and tensin homolog deleted from chromosome 10]], [[PTEN]])-[[ミオシンV]]相互作用 || ||2009 || 2 || <ref><pubmed>19767745</pubmed></ref>
|-
|rowspan="8" | [[プロテアーゼ]] || [[カスパーゼ-3]] ||EGFP-DEVD-EBFP|| 1998 || 1 || <ref><pubmed>9518501</pubmed></ref>
|-
| [[カスパーゼ-8]] ||CFP-c3-YFP-c6-mRFP|| 2002 || 1 || <ref><pubmed>12409609</pubmed></ref>
|-
| [[カスパーゼ-9]] ||SCAT9|| 2011 || 1 || <ref><pubmed>21637712</pubmed></ref>
|-
| [[カスパーゼ-7]] ||VDEVDc|| 2006 || 1 || <ref><pubmed>17946841</pubmed></ref>
|-
| [[マトリックスメタロプロテアーゼ]] ([[MMP]]) ||YFP-MSS-CFP<sup>display</sup>, MTI-MMP-FRET biosensor|| 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref>
|-
| [[wj:第Xa因子|第Xa因子]] || ||1996 || 1 || <ref><pubmed>8707050</pubmed></ref>
|-
|[[カルパイン]]活性||pYSCS|| 2000 || 1 || <ref><pubmed>10688895</pubmed></ref>
|-
| [[プレセニリン]] ||GFP-PSI-RFP|| 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref>
|-
|rowspan="5" | その他 ||細胞膜張力センサー ||stFRET|| 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref>
|-
| [[膜電位]] ||VSFP, Mermaid, ArcLight, VSFP-Butterfly|| 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref><ref><pubmed> 23868559</pubmed></ref>
|-
| [[ミオシンII]] ||GSldCB|| 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref>
|-
| [[wj:ヒト免疫不全ウイルス|ヒト免疫不全ウイルス]]Revタンパク質 ||YRGnC-11ad|| 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref>
|-
|| [[wj:酸化還元|酸化還元]] ||Redoxfluor, Gaskins|| 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
|}
 
The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.
 
<references />

2013年12月30日 (月) 19:56時点における版

「https://bsd.neuroinf.jp/w/index.php?title=Test&oldid=24314」から取得