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| (2人の利用者による、間の84版が非表示) |
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| {| class="wikitable"
| | [[ファイル:Q7RTS3.pdb|サムネイル|'''図2. ヒトPTF1A立体構造'''<br>AlphaFold予測（Q7RTS3）]] |
| |+ 表1．
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| |-
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| | Classification||Target ||Year||Probe design ||References
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| | Small molecule || カルシウム || 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref>
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| |-
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| | Small molecule || サイクリックGMP (cGMP) || 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref>
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| |-
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| | Small molecule || サイクリックAMP (cAMP) || 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>
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| |-
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| | Small molecule || イノシトール3リン酸 (IP3) || 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>
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| |-
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| | Small molecule || 一酸化窒素 (NO) || 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
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| |-
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| | Small molecule || アデノシン3リン酸 (ATP) || 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
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| |-
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| | Small molecule || エストロゲン || 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref>
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| |-
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| | Small molecule || アンドロゲン || 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref>
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| |-
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| | Small molecule || グルココルチコイド受容体リガンド || 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref>
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| |-
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| | Small molecule || 神経成長因子 || 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
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| |-
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| | Small molecule || 核内受容体 || 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
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| |-
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| | Small molecule || O-N-アセチルグルコサミン (O-GlcNAc) || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref>
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| |-
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| | Small molecule || ビタミンA (レチノイン酸) || 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref>
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| |-
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| | Small molecule || モリブデン酸 || 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref>
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| |-
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| | Small molecule || グルタミン酸 || 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref>
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| |-
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| | Small molecule || Zn<sup>2+</sup> || 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
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| |-
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| | Small molecule || Cl<sup>-</sup> || 2000 || other || <ref><pubmed>11055428</pubmed></ref>
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| |-
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| | Small molecule || 水素イオン濃度 (pH) || 2001 || other || <ref><pubmed>11716495</pubmed></ref>
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| |-
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| | Small molecule || グルコース || 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref>
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| |-
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| | Small molecule || Maltose || 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref>
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| |-
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| | Small molecule || Ribose || 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref>
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| |-
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| | Kinase || Calcium/Calmodulin-dependent protein kinase II (CaMKII) || 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref>
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| |-
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| | Kinase || Src || 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref>
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| |-
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| | Kinase || Protein kinase C (PKC) || 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref>
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| |-
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| | Kinase || Protein kinase D (PKD) || 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref>
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| |-
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| | Kinase || Protein kinase A (PKA) || 2000, 2001 || 3-3 || <ref><pubmed>10700148, 11752448</pubmed></ref>
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| |- Table 1 A list of genetically encoded FRET probes.
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| | Kinase || Abl || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
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| |-
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| | Kinase || Bcr-Abl || 2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref>
| |
| |- The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.
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| | Kinase || c-Raf || 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref>
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| |-
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| | Kinase || PAK1 || 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref>
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| |-
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| | Kinase || B-raf || 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref>
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| |-
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| | Kinase || ZAP-70 || 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref>
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| |-
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| | Kinase || Akt || 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref><pubmed> 17407381</pubmed></ref>
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| |-
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| | Kinase || ERK || 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref>
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| |-
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| | Kinase || Insulin receptor || 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref>
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| |-
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| | Kinase || Epidermal Growth factor receptor (EGFR) || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
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| |-
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| | Kinase || Ataxia telangiectasia mutated (ATM) || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref>
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| |-
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| | Kinase || Aurora B kinase || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref>
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| |-
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| | Kinase || Cyclin B1-CDK1 || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref>
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| |-
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| | Kinase || Myosine light chain kinase || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
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| |-
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| | Kinase || JNK || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref><pubmed> 21976697</pubmed></ref>
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| |-
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| | Kinase || RSK || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref>
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| |-
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| | Kinase || S6K || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref>
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| |-
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| | Kinase || Focal Adhesion Kinase (FAK) || 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
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| |-
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| | Kinase || PLK1 || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref>
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| |-
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| | Kinase || SAP3K || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref>
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| |-
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| | Kinase || DAPK1 || 2011 || 3-1 || <ref><pubmed>21506563</pubmed></ref>
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| |-
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| | Phosphatase || Calcineurin || 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref>
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| |-
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| | Small GTPase || Ras || 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref><pubmed> 11429608</pubmed></ref>
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| |-
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| | Small GTPase || Rap || 2001 || 3-2 || <ref><pubmed>11429608</pubmed></ref>
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| |-
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| | Small GTPase || Rac || 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref>
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| |-
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| | Small GTPase || Rab5 || 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref>
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| |-
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| | Small GTPase || Rho || 2003, 2011 || 3-2, 2 || <ref><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref>
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| |-
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| | Small GTPase || Cdc42 || 2004, 2011 || 3-2, 2 || <ref><pubmed>14570905</pubmed></ref><ref><pubmed> 21423166</pubmed></ref>
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| |-
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| | Small GTPase || Ral || 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref>
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| |-
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| | Small GTPase || TC10 || 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref>
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| |-
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| | Signal transduction || RCC1(GEF of Ran) || 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref>
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| |-
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| | Signal transduction || CrkII phosphorylation || 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref>
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| |-
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| | Signal transduction || N-WASP || 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
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| |-
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| | Signal transduction || Adrenergic receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref>
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| |-
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| | Signal transduction || Parathyroid hormone receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref>
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| |-
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| | Signal transduction || Plasma membrane Calcium pump || 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
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| |-
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| | Acetylation || Histone acetylation || 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref>
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| |-
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| | Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) || 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref>
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| |-
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| | Lipid || Phosphatidylinositol (4,5)-bisphosphate (PIP2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
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| |-
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| | Lipid || Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
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| |-
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| | Lipid || Phosphatidylinositol 4-phosphate (PI4P) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
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| |-
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| | Lipid || Phosphatidic acid || 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref>
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| |-
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| | Lipid || Diacylglycerol (DAG) || 2006, 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref><ref><pubmed> 16990811</pubmed></ref>
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| |-
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| | Protein interaction || Actin || 2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref>
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| |-
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| | Protein interaction || PDK1-Akt interaction || 2007 || 2 || <ref><pubmed>17407381</pubmed></ref>
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| |-
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| | Protein interaction || Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref>
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| |-
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| | Protein interaction || Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG || 2010 || 2 || <ref><pubmed>20622991</pubmed></ref>
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| |-
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| | Protein interaction || Cofiin-actin interaction || 2008 || 2 || <ref><pubmed>17993279</pubmed></ref>
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| |-
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| | Protein interaction || PTEN-Myosin V interaction || 2009 || 2 || <ref><pubmed>19767745</pubmed></ref>
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| |-
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| | Protease || Caspase-3 || 1998 || 1 || <ref><pubmed>9518501</pubmed></ref>
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| |-
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| | Protease || Caspase-8 || 2002 || 1 || <ref><pubmed>12409609</pubmed></ref>
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| |-
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| | Protease || Caspase-9 || 2011 || 1 || <ref><pubmed>21637712</pubmed></ref>
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| |-
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| | Protease || Caspase-7 || 2006 || 1 || <ref><pubmed>17946841</pubmed></ref>
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| |-
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| | Protease || Matrix Metalloproteinase (MMP) || 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref>
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| |-
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| | Protease || Protease activity (Factor Xa) || 1996 || 1 || <ref><pubmed>8707050</pubmed></ref>
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| |-
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| | Protease || Calpain activity || 2000 || 1 || <ref><pubmed>10688895</pubmed></ref>
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| |-
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| | Protease || Presenilin || 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref>
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| |-
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| | Other || Strain sensor || 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref>
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| |-
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| | Other || Membrane potential || 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref>
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| |-
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| | Other || Myosin II || 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref>
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| |-
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| | Other || HIV Rev protein || 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref>
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| |-
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| | Other || Redox || 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
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| |-
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| }
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| <references /> | |