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{| class="wikitable"
<ref name=Krapp1996><pubmed>8861960</pubmed></ref>
|+ 表1．
<ref name=Knoefler1996><pubmed>8703005</pubmed></ref>
|-
<ref name=Rose2001><pubmed>11562365</pubmed></ref>
| Classification||Target ||Year||Probe design ||References
<ref name=Krapp1998><pubmed>9851981</pubmed></ref>
|-
<ref name=Kawaguchi2002><pubmed>12185368</pubmed></ref>
| Small molecule || カルシウム || 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref>
<ref name=Sellick2004><pubmed>15543146</pubmed></ref>
|-
<ref name=Sellick2003><pubmed>14514650</pubmed></ref>
| Small molecule || サイクリックGMP (cGMP) || 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref>  
<ref name=Hoveyda1999><pubmed>10507728</pubmed></ref>
|-
<ref name=Masui2008><pubmed>18606784</pubmed></ref>
| Small molecule || サイクリックAMP (cAMP) || 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>  
<ref name=Pan2013><pubmed>23325761</pubmed></ref>
|-
<ref name=Burlison2008><pubmed>18294628</pubmed></ref>
| Small molecule || イノシトール3リン酸 (IP3) || 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>  
<ref name=AlShammari2011><pubmed>21749365</pubmed></ref>
|-
<ref name=Adell2000><pubmed>10768861</pubmed></ref>
| Small molecule || 一酸化窒素 (NO) || 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
<ref name=Masui2007><pubmed>17938243</pubmed></ref>
|-
<ref name=Magnuson2013><pubmed>23823474</pubmed></ref>
| Small molecule || アデノシン3リン酸 (ATP) || 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
<ref name=Fujitani2017><pubmed>28420858</pubmed></ref>
|-
<ref name=VeiteSchmahl2017><pubmed>28697176</pubmed></ref>
| Small molecule || エストロゲン || 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref>
<ref name=Hingorani2003><pubmed>14706336</pubmed></ref>
|-
<ref name=Obata2001><pubmed>11318877</pubmed></ref>
| Small molecule || アンドロゲン || 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref>
<ref name=Hoshino2005><pubmed>16039563</pubmed></ref>
|-
<ref name=Hoshino2006><pubmed>16997750</pubmed></ref>
| Small molecule || グルココルチコイド受容体リガンド || 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref>
<ref name=Wullimann2011><pubmed>21559349</pubmed></ref>
|-
<ref name=Yamada2014><pubmed>24695699</pubmed></ref>
| Small molecule || 神経成長因子 || 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
<ref name=Seto2014><pubmed>24535035</pubmed></ref>
|-
<ref name=Pascual2007><pubmed>17360405</pubmed></ref>
| Small molecule || 核内受容体 || 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
<ref name=Millen2008><pubmed>18513948</pubmed></ref>
|-
<ref name=Achim2014><pubmed>24196748</pubmed></ref>
| Small molecule || O-N-アセチルグルコサミン (O-GlcNAc) || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref>
<ref name=Lowenstein2023><pubmed>35262281</pubmed></ref>
|-
<ref name=BenArie1997><pubmed>9367153</pubmed></ref>
| Small molecule || ビタミンA (レチノイン酸) || 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref>
<ref name=Machold2005><pubmed>16202705</pubmed></ref>
|-
<ref name=Wang2005><pubmed>16202707</pubmed></ref>
| Small molecule || モリブデン酸 || 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref>
<ref name=Glasgow2005><pubmed>16291784</pubmed></ref>
|-
<ref name=Hori2012><pubmed>22830054</pubmed></ref>
| Small molecule || グルタミン酸 || 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref>
<ref name=Fujitani2006><pubmed>17075007</pubmed></ref>
|-
<ref name=Nakhai2007><pubmed>17301087</pubmed></ref>
| Small molecule || Zn<sup>2+</sup> || 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
<ref name=Dullin2007><pubmed>17910758</pubmed></ref>
|-
<ref name=Fujiyama2009><pubmed>19439493</pubmed></ref>
| Small molecule || Cl<sup>-</sup> || 2000 || other || <ref><pubmed>11055428</pubmed></ref>
<ref name=Yamada2007><pubmed>17928434</pubmed></ref>
|-
<ref name=Aldinger2008><pubmed>18184775</pubmed></ref>
| Small molecule || 水素イオン濃度 (pH) || 2001 || other || <ref><pubmed>11716495</pubmed></ref>
<ref name=Fujiyama2018><pubmed>29972793</pubmed></ref>
|-
<ref name=Horie2018><pubmed>30228204</pubmed></ref>
| Small molecule || グルコース || 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref>
<ref name=Russ2015><pubmed>25878276</pubmed></ref>
|-
<ref name=Uhlen2015><pubmed>25613900</pubmed></ref>
| Small molecule || Maltose || 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref>
<ref name=Duque2022><pubmed>34125483</pubmed></ref>
|-
<ref name=Beres2006><pubmed>16354684</pubmed></ref>
| Small molecule || Ribose || 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref>
<ref name=Masui2010><pubmed>20398665</pubmed></ref>
|-
<ref name=Hori2008><pubmed>18198335</pubmed></ref>
| Kinase || Calcium/Calmodulin-dependent protein kinase II (CaMKII) || 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref>
<ref name=Lelievre2011><pubmed>21839069</pubmed></ref>
|-
<ref name=Hanoun2014><pubmed>25355311</pubmed></ref>
| Kinase || Src || 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref>
<ref name=Rodolosse2009><pubmed>18834332</pubmed></ref>
|-
<ref name=Jin2019><pubmed>30470852</pubmed></ref>
| Kinase || Protein kinase C (PKC) || 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref>
<ref name=Hanotel2014><pubmed>24370451</pubmed></ref>
|-
<ref name=Whittaker2021><pubmed>34730112</pubmed></ref>
| Kinase || Protein kinase D (PKD) || 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref>
<ref name=Chang2013><pubmed>23639443</pubmed></ref>
|-
<ref name=Watanabe2015><pubmed>25995483</pubmed></ref>
| Kinase || Protein kinase A (PKA) || 2000, 2001 || 3-3 || <ref><pubmed>10700148, 11752448</pubmed></ref>
<ref name=Jin2015><pubmed>25966682</pubmed></ref>
|- Table 1 A list of genetically encoded FRET probes.
<ref name=Nishida2010><pubmed>19887377</pubmed></ref>
| Kinase || Abl || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
<ref name=Henke2009><pubmed>19641016</pubmed></ref>
|-
<ref name=Wiebe2007><pubmed>17403901</pubmed></ref>
| Kinase || Bcr-Abl || 2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref>
<ref name=Meredith2013><pubmed>23754747</pubmed></ref>
|- The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.
<ref name=Schaffer2010><pubmed>20627083</pubmed></ref>
| Kinase || c-Raf || 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref>
<ref name=AhnfeltRonne2012><pubmed>22096075</pubmed></ref>
|-
<ref name=Mona2016><pubmed>27350561</pubmed></ref>
| Kinase || PAK1 || 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref>
<ref name=Meredith2009><pubmed>19741120</pubmed></ref>
|-
<ref name=Liu2013><pubmed>23652001</pubmed></ref>
| Kinase || B-raf || 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref>
<ref name=Ito2023><pubmed>37248264</pubmed></ref>
|-
<ref name=Millen2014><pubmed>24733890</pubmed></ref>
| Kinase || ZAP-70 || 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref>
<ref name=Huang2008><pubmed>18634777</pubmed></ref>
|-
<ref name=Bikoff2016><pubmed>26949184</pubmed></ref>
| Kinase || Akt || 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref><pubmed> 17407381</pubmed></ref>
<ref name=Zhang2017><pubmed>29045835</pubmed></ref>
|-
<ref name=Escalante2020><pubmed>33238109</pubmed></ref>
| Kinase || ERK || 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref>
<ref name=Jusuf2009><pubmed>19732413</pubmed></ref>
|-
<ref name=Jusuf2011><pubmed>21325522</pubmed></ref>
| Kinase || Insulin receptor || 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref>
<ref name=Mazurier2014><pubmed>24643195</pubmed></ref>
|-
<ref name=Bessodes2017><pubmed>28863786</pubmed></ref>
| Kinase || Epidermal Growth factor receptor (EGFR) || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
<ref name=RazyKrajka2012><pubmed>22642675</pubmed></ref>
|-
<ref name=Maricich2009><pubmed>19741118</pubmed></ref>
| Kinase || Ataxia telangiectasia mutated (ATM) || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref>
<ref name=Bae2009><pubmed>19371731</pubmed></ref>
|-
<ref name=Elliott2023><pubmed>37055006</pubmed></ref>
| Kinase || Aurora B kinase || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref>
<ref name=Iskusnykh2016><pubmed>26937009</pubmed></ref>
|-
<ref name=Kohl2012><pubmed>22539838</pubmed></ref>
| Kinase || Cyclin B1-CDK1 || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref>
<ref name=Fukuda2008><pubmed>18591390</pubmed></ref>
|-
<ref name=Sakikubo2018><pubmed>30361559</pubmed></ref>
| Kinase || Myosine light chain kinase || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
|-
| Kinase || JNK || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref><pubmed> 21976697</pubmed></ref>
|-
| Kinase || RSK || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref>
|-
| Kinase || S6K || 2011 || 3-3 || <ref><pubmed>21976697</pubmed></ref>
|-
| Kinase || Focal Adhesion Kinase (FAK) || 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
|-
| Kinase || PLK1 || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref>
|-
| Kinase || SAP3K || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref>
|-
| Kinase || DAPK1 || 2011 || 3-1 || <ref><pubmed>21506563</pubmed></ref>
|-
| Phosphatase || Calcineurin || 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref>
|-
| Small GTPase || Ras || 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref><pubmed> 11429608</pubmed></ref>
|-
| Small GTPase || Rap || 2001 || 3-2 || <ref><pubmed>11429608</pubmed></ref>
|-
| Small GTPase || Rac || 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref>
|-
| Small GTPase || Rab5 || 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref>
|-
| Small GTPase || Rho || 2003, 2011 || 3-2, 2 || <ref><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref>
|-
| Small GTPase || Cdc42 || 2004, 2011 || 3-2, 2 || <ref><pubmed>14570905</pubmed></ref><ref><pubmed> 21423166</pubmed></ref>
|-
| Small GTPase || Ral || 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref>
|-
| Small GTPase || TC10 || 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref>
|-
| Signal transduction || RCC1(GEF of Ran) || 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref>
|-
| Signal transduction || CrkII phosphorylation || 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref>
|-
| Signal transduction || N-WASP || 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
|-
| Signal transduction || Adrenergic receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref>
|-
| Signal transduction || Parathyroid hormone receptor || 2003 || 3-1 || <ref><pubmed>12808462</pubmed></ref>
|-
| Signal transduction || Plasma membrane Calcium pump || 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
|-
| Acetylation || Histone acetylation || 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref>
|-
| Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) || 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref>
|-
| Lipid || Phosphatidylinositol (4,5)-bisphosphate (PIP2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
|-
| Lipid || Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
|-
| Lipid || Phosphatidylinositol 4-phosphate (PI4P) || 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref>
|-
| Lipid || Phosphatidic acid || 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref>
|-
| Lipid || Diacylglycerol (DAG) || 2006, 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref><ref><pubmed> 16990811</pubmed></ref>
|-
| Protein interaction || Actin || 2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref>
|-
| Protein interaction || PDK1-Akt interaction || 2007 || 2 || <ref><pubmed>17407381</pubmed></ref>
|-
| Protein interaction || Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref>
|-
| Protein interaction || Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG || 2010 || 2 || <ref><pubmed>20622991</pubmed></ref>
|-
| Protein interaction || Cofiin-actin interaction || 2008 || 2 || <ref><pubmed>17993279</pubmed></ref>
|-
| Protein interaction || PTEN-Myosin V interaction || 2009 || 2 || <ref><pubmed>19767745</pubmed></ref>
|-
| Protease || Caspase-3 || 1998 || 1 || <ref><pubmed>9518501</pubmed></ref>
|-
| Protease || Caspase-8 || 2002 || 1 || <ref><pubmed>12409609</pubmed></ref>
|-
| Protease || Caspase-9 || 2011 || 1 || <ref><pubmed>21637712</pubmed></ref>
|-
| Protease || Caspase-7 || 2006 || 1 || <ref><pubmed>17946841</pubmed></ref>
|-
| Protease || Matrix Metalloproteinase (MMP) || 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref>
|-
| Protease || Protease activity (Factor Xa) || 1996 || 1 || <ref><pubmed>8707050</pubmed></ref>
|-
| Protease || Calpain activity || 2000 || 1 || <ref><pubmed>10688895</pubmed></ref>
|-
| Protease || Presenilin || 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref>
|-
| Other || Strain sensor || 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref>
|-
| Other || Membrane potential || 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref>
|-
| Other || Myosin II || 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref>
|-
| Other || HIV Rev protein || 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref>
|-
| Other || Redox || 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
|-
}
 
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