「テンプレート:PBB/6722」の版間の差分
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2012年5月8日 (火) 15:28時点における最新版
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2012年5月8日 (火) 15:28時点における最新版
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Tfuruya
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2012年5月8日 (火) 15:28時点における最新版
Serum response factor (c-fos serum response element-binding transcription factor)
PDB
rendering based on 1SRS. Protein Data Bank Japanwebページより出典
Available structures
PDB
1HBX
,
1K6O
,
1SRS
Identifiers
Symbols
SRF
; MCM1
External IDs
OMIM
:
600589
MGI
:
106658
HomoloGene
:
31135
GeneCards
:
SRF Gene
Gene Ontology
Molecular function
•
RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
•
RNA polymerase II transcription factor binding transcription factor activity
•
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
•
chromatin binding
•
sequence-specific DNA binding transcription factor activity
•
sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
•
protein binding
•
transcription factor binding
•
serum response element binding
•
protein homodimerization activity
•
sequence-specific DNA binding
Cellular component
•
nuclear chromatin
•
nucleus
•
nucleolus
•
cytoplasm
•
cytoplasm
•
endoplasmic reticulum
Biological process
•
patterning of blood vessels
•
in utero embryonic development
•
mesoderm formation
•
neuron migration
•
trophectodermal cell differentiation
•
heart looping
•
morphogenesis of an epithelial sheet
•
cell migration involved in sprouting angiogenesis
•
leukocyte differentiation
•
transcription from RNA polymerase II promoter
•
actin filament organization
•
cell-matrix adhesion
•
multicellular organismal development
•
gastrulation
•
heart development
•
long-term memory
•
negative regulation of cell proliferation
•
associative learning
•
response to toxin
•
response to hormone stimulus
•
epithelial structure maintenance
•
positive regulation of transcription via serum response element binding
•
hippocampus development
•
tangential migration from the subventricular zone to the olfactory bulb
•
contractile actin filament bundle assembly
•
regulation of cell adhesion
•
platelet activation
•
platelet formation
•
negative regulation of cell migration
•
neuron projection development
•
regulation of water loss via skin
•
response to cytokine stimulus
•
response to cytokine stimulus
•
megakaryocyte development
•
dorsal aorta morphogenesis
•
stress fiber assembly
•
skin morphogenesis
•
positive thymic T cell selection
•
sarcomere organization
•
positive regulation of cell differentiation
•
positive regulation of transcription from RNA polymerase II promoter
•
positive regulation of smooth muscle contraction
•
muscle cell homeostasis
•
developmental growth
•
neuron development
•
erythrocyte development
•
regulation of smooth muscle cell differentiation
•
positive regulation of filopodium assembly
•
cardiac myofibril assembly
•
angiogenesis involved in wound healing
•
hemopoietic stem cell differentiation
•
positive regulation of transcription initiation from RNA polymerase II promoter
•
long term synaptic depression
•
heart trabecula formation
•
cardiac vascular smooth muscle cell differentiation
•
eyelid development in camera-type eye
•
tight junction assembly
•
primitive streak formation
•
epithelial cell-cell adhesion
•
cellular senescence
Sources:
Amigo
/
QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species
Human
Mouse
Entrez
6722
20807
Ensembl
ENSG00000112658
ENSMUSG00000015605
UniProt
P11831
Q9JM73
RefSeq (mRNA)
NM_003131.2
NM_020493.2
RefSeq (protein)
NP_003122.1
NP_065239.1
Location (UCSC)
Chr 6:
43.14 – 43.15 Mb
Chr 17:
46.68 – 46.69 Mb
PubMed
search
[1]
[2]
カテゴリ
:
Human proteins
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