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{| class="wikitable"
<ref name=Krapp1996><pubmed>8861960</pubmed></ref>
|+ 表1．
<ref name=Knoefler1996><pubmed>8703005</pubmed></ref>
|-
<ref name=Rose2001><pubmed>11562365</pubmed></ref>
| 分類||対象||プローブ名||年||プローブデザイン||参考文献
<ref name=Krapp1998><pubmed>9851981</pubmed></ref>
|-
<ref name=Kawaguchi2002><pubmed>12185368</pubmed></ref>
|rowspan="21" | 生体内小分子|| [[カルシウム]] ||Cameleon|| 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref>
<ref name=Sellick2004><pubmed>15543146</pubmed></ref>
|-
<ref name=Sellick2003><pubmed>14514650</pubmed></ref>
|[[サイクリックGMP]] ([[cGMP]]) ||CGY, Cygnet, pGES-DE2, cGi|| 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref>  
<ref name=Hoveyda1999><pubmed>10507728</pubmed></ref>
|-
<ref name=Masui2008><pubmed>18606784</pubmed></ref>
|[[サイクリックAMP]] ([[cAMP]]) ||Epac|| 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>  
<ref name=Pan2013><pubmed>23325761</pubmed></ref>
|-
<ref name=Burlison2008><pubmed>18294628</pubmed></ref>
|[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) ||LIBRA, Fretino, FIRE|| 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>  
<ref name=AlShammari2011><pubmed>21749365</pubmed></ref>
|-
<ref name=Adell2000><pubmed>10768861</pubmed></ref>
|[[一酸化窒素]] ([[NO]]) ||NOA-1, Piccell|| 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
<ref name=Masui2007><pubmed>17938243</pubmed></ref>
|-
<ref name=Magnuson2013><pubmed>23823474</pubmed></ref>
|[[アデノシン3リン酸]] ([[ATP]]) ||A Team 1.03-nD/nA|| 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
<ref name=Fujitani2017><pubmed>28420858</pubmed></ref>
|-
<ref name=VeiteSchmahl2017><pubmed>28697176</pubmed></ref>
|[[エストロゲン]] ||SCCoR|| 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref>
<ref name=Hingorani2003><pubmed>14706336</pubmed></ref>
|-
<ref name=Obata2001><pubmed>11318877</pubmed></ref>
|[[アンドロゲン]] ||Ficaro|| 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref>
<ref name=Hoshino2005><pubmed>16039563</pubmed></ref>
|-
<ref name=Hoshino2006><pubmed>16997750</pubmed></ref>
|[[グルココルチコイド受容体]]リガンド ||GLUCOCOR|| 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref>
<ref name=Wullimann2011><pubmed>21559349</pubmed></ref>
|-
<ref name=Yamada2014><pubmed>24695699</pubmed></ref>
|[[神経成長因子]] ||ECaus|| 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
<ref name=Seto2014><pubmed>24535035</pubmed></ref>
|-
<ref name=Pascual2007><pubmed>17360405</pubmed></ref>
|[[核内受容体]] ||conpro|| 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
<ref name=Millen2008><pubmed>18513948</pubmed></ref>
|-
<ref name=Achim2014><pubmed>24196748</pubmed></ref>
|[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref>
<ref name=Lowenstein2023><pubmed>35262281</pubmed></ref>
|-
<ref name=BenArie1997><pubmed>9367153</pubmed></ref>
|[[ビタミンA]] ([[レチノイン酸]]) ||GEPRAS|| 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref>
<ref name=Machold2005><pubmed>16202705</pubmed></ref>
|-
<ref name=Wang2005><pubmed>16202707</pubmed></ref>
|[[wj:モリブデン酸|モリブデン酸]] ||MolyProbe|| 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref>
<ref name=Glasgow2005><pubmed>16291784</pubmed></ref>
|-
<ref name=Hori2012><pubmed>22830054</pubmed></ref>
|[[グルタミン酸]] ||FLIPE|| 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref>
<ref name=Fujitani2006><pubmed>17075007</pubmed></ref>
|-
<ref name=Nakhai2007><pubmed>17301087</pubmed></ref>
|[[wj:亜鉛|Zn<sup>2+</sup>]] ||eCALWY-1|| 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
<ref name=Dullin2007><pubmed>17910758</pubmed></ref>
|-
<ref name=Fujiyama2009><pubmed>19439493</pubmed></ref>
|[[wj:塩素|Cl<sup>-</sup>]] ||Clomeleon|| 2000 || other || <ref><pubmed>11055428</pubmed></ref>
<ref name=Yamada2007><pubmed>17928434</pubmed></ref>
|-
<ref name=Aldinger2008><pubmed>18184775</pubmed></ref>
|[[wj:水素イオン濃度|水素イオン濃度]] (pH) ||GFpH, YFpH|| 2001 || other || <ref><pubmed>11716495</pubmed></ref>
<ref name=Fujiyama2018><pubmed>29972793</pubmed></ref>
|-
<ref name=Horie2018><pubmed>30228204</pubmed></ref>
|[[wj:グルコース|グルコース]] ||FLIPglu|| 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref>
<ref name=Russ2015><pubmed>25878276</pubmed></ref>
|-
<ref name=Uhlen2015><pubmed>25613900</pubmed></ref>
|[[wj:マルトース|マルトース]]||FLIPmal|| 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref>
<ref name=Duque2022><pubmed>34125483</pubmed></ref>
|-
<ref name=Beres2006><pubmed>16354684</pubmed></ref>
|[[wj:リボース|リボース]]||FLIPrib|| 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref>
<ref name=Masui2010><pubmed>20398665</pubmed></ref>
|-
<ref name=Hori2008><pubmed>18198335</pubmed></ref>
|rowspan="26" | キナーゼ || [[カルシウム/カルモジュリン依存製タンパク質キナーゼII]] ([[CaMKII]]) ||Camui α, green-Camui α, Camk2a reporter|| 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref>
<ref name=Lelievre2011><pubmed>21839069</pubmed></ref>
|-
<ref name=Hanoun2014><pubmed>25355311</pubmed></ref>
| [[Src]] ||Srcus|| 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref>
<ref name=Rodolosse2009><pubmed>18834332</pubmed></ref>
|-
<ref name=Jin2019><pubmed>30470852</pubmed></ref>
| Protein kinase C (PKC) ||CKAR, CY-PKCdelta|| 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref>
<ref name=Hanotel2014><pubmed>24370451</pubmed></ref>
|-
<ref name=Whittaker2021><pubmed>34730112</pubmed></ref>
| Protein kinase D (PKD) ||DKAR|| 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref>
<ref name=Chang2013><pubmed>23639443</pubmed></ref>
|-
<ref name=Watanabe2015><pubmed>25995483</pubmed></ref>
| Protein kinase A (PKA) ||ART, AKAR|| 2000, 2001 || 3-3 || <ref><pubmed>10700148</pubmed></ref><ref><pubmed>11752448</pubmed></ref>
<ref name=Jin2015><pubmed>25966682</pubmed></ref>
|- Table 1 A list of genetically encoded FRET probes.
<ref name=Nishida2010><pubmed>19887377</pubmed></ref>
| Abl ||Picchu|| 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
<ref name=Henke2009><pubmed>19641016</pubmed></ref>
|-
<ref name=Wiebe2007><pubmed>17403901</pubmed></ref>
| Bcr-Abl ||Bcr-Abl activity sensor||2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref>
<ref name=Meredith2013><pubmed>23754747</pubmed></ref>
|-
<ref name=Schaffer2010><pubmed>20627083</pubmed></ref>
| c-Raf ||Prin-cRaf|| 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref>
<ref name=AhnfeltRonne2012><pubmed>22096075</pubmed></ref>
|-
<ref name=Mona2016><pubmed>27350561</pubmed></ref>
| PAK1 ||Pakabi|| 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref>
<ref name=Meredith2009><pubmed>19741120</pubmed></ref>
|-
<ref name=Liu2013><pubmed>23652001</pubmed></ref>
| B-raf ||Prin-Braf|| 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref>
<ref name=Ito2023><pubmed>37248264</pubmed></ref>
|-
<ref name=Millen2014><pubmed>24733890</pubmed></ref>
| ZAP-70 ||ROZA|| 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref>
<ref name=Huang2008><pubmed>18634777</pubmed></ref>
|-
<ref name=Bikoff2016><pubmed>26949184</pubmed></ref>
| Akt ||Aktus, BKAR, Akind|| 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref><pubmed> 17407381</pubmed></ref>
<ref name=Zhang2017><pubmed>29045835</pubmed></ref>
|-
<ref name=Escalante2020><pubmed>33238109</pubmed></ref>
| ERK ||Miu2, Erkus, EKAR|| 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref>
<ref name=Jusuf2009><pubmed>19732413</pubmed></ref>
|-
<ref name=Jusuf2011><pubmed>21325522</pubmed></ref>
| Insulin receptor ||Phocus|| 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref>
<ref name=Mazurier2014><pubmed>24643195</pubmed></ref>
|-
<ref name=Bessodes2017><pubmed>28863786</pubmed></ref>
| Epidermal Growth factor receptor (EGFR) || ||2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
<ref name=RazyKrajka2012><pubmed>22642675</pubmed></ref>
|-
<ref name=Maricich2009><pubmed>19741118</pubmed></ref>
| Ataxia telangiectasia mutated (ATM) || || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref>
<ref name=Bae2009><pubmed>19371731</pubmed></ref>
|-
<ref name=Elliott2023><pubmed>37055006</pubmed></ref>
| Aurora B kinase || || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref>
<ref name=Iskusnykh2016><pubmed>26937009</pubmed></ref>
|-
<ref name=Kohl2012><pubmed>22539838</pubmed></ref>
| Cyclin B1-CDK1 || || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref>
<ref name=Fukuda2008><pubmed>18591390</pubmed></ref>
|-
<ref name=Sakikubo2018><pubmed>30361559</pubmed></ref>
| Myosine light chain kinase ||MLCK-FIP || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
|-
| JNK ||JNKAR1, JUNKAR1EV || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref>
|-
| RSK ||Eevee-RSK|| 2011 || 3-3 || <ref name=ref21976697></ref>
|-
| S6K ||Eevee-S6K|| 2011 || 3-3 || <ref name=ref21976697></ref>
|-
| Focal Adhesion Kinase (FAK) ||CYFAK413, FERM-sensor|| 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
|-
| PLK1 || || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref>
|-
| SAP3K || || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref>
|-
| DAPK1 ||DAPK1(334)-F40|| 2011 || 3-1 || <ref><pubmed>21506563</pubmed></ref>
|-
| ホスファターゼ || Calcineurin ||CaNAR1|| 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref>
|-
|rowspan="8" | Small GTPase || Ras ||Raichu-Ras, Fras|| 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref>
|-
| Rap ||Raichu-Rap|| 2001 || 3-2 || <ref name=ref11429608></ref>
|-
| Rac ||Raichu-Rac1|| 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref>
|-
| Rab5 ||Raichu-Rab5|| 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref>
|-
| Rho ||Raichu-RhoA|| 2003, 2011 || 3-2, 2 || <ref><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref>
|-
| Cdc42 ||Raichu-cdc42|| 2004, 2011 || 3-2, 2 || <ref><pubmed>14570905</pubmed></ref><ref><pubmed> 21423166</pubmed></ref>
|-
| Ral ||Raichu-Ral|| 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref>
|-
| TC10 ||Raichu-TC10|| 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref>
|-
|rowspan="6" | Signal transduction || RCC1(GEF of Ran) ||CFP-RCC1-YFP|| 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref>
|-
| CrkII phosphorylation ||Picchu|| 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref>
|-
| N-WASP ||Stinger|| 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
|-
| Adrenergic receptor ||α<sub>2A</sub>AR-cam|| 2003 || 3-1 || <ref name=ref12808462><pubmed>12808462</pubmed></ref>
|-
| Parathyroid hormone receptor ||PTHR-cam|| 2003 || 3-1 || <ref name=ref12808462></ref>
|-
| Plasma membrane Calcium pump ||BFP-PMCA-GFP|| 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
|-
| Acetylation || Histone acetylation ||Histac|| 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref>
|-
|rowspan="6" | Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) ||Fllip, FLIMPA|| 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref>
|-
| Phosphatidylinositol (4,5)-bisphosphate (PIP2) ||Pippi-PI(4,5)P<sub>2</sub>|| 2008 || 3-4 || <ref name=ref18685081><pubmed>18685081</pubmed></ref>
|-
| Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) ||Pippi-PI(3,4)P<sub>2</sub>|| 2008 || 3-4 || <ref name=ref18685081></ref>
|-
| Phosphatidylinositol 4-phosphate (PI4P) ||Pippi-PI(4)P|| 2008 || 3-4 || <ref name=ref18685081></ref>
|-
| Phosphatidic acid ||Pii|| 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref>
|-
| Diacylglycerol (DAG) ||Daglas, DIGDA|| 2006, 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref><ref><pubmed> 16990811</pubmed></ref>
|-
|rowspan="6" | Protein interaction || Actin || ||2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref>
|-
| PDK1-Akt interaction || ||2007 || 2 || <ref><pubmed>17407381</pubmed></ref>
|-
| Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction || || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref>
|-
| Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG || ||2010 || 2 || <ref><pubmed>20622991</pubmed></ref>
|-
| Cofiin-actin interaction || ||2008 || 2 || <ref><pubmed>17993279</pubmed></ref>
|-
| PTEN-Myosin V interaction || ||2009 || 2 || <ref><pubmed>19767745</pubmed></ref>
|-
|rowspan="8" | Protease || Caspase-3 ||EGFP-DEVD-EBFP|| 1998 || 1 || <ref><pubmed>9518501</pubmed></ref>
|-
| Caspase-8 ||CFP-c3-YFP-c6-mRFP|| 2002 || 1 || <ref><pubmed>12409609</pubmed></ref>
|-
| Caspase-9 ||SCAT9|| 2011 || 1 || <ref><pubmed>21637712</pubmed></ref>
|-
| Caspase-7 ||VDEVDc|| 2006 || 1 || <ref><pubmed>17946841</pubmed></ref>
|-
| Matrix Metalloproteinase (MMP) ||YFP-MSS-CFP<sup>display</sup>, MTI-MMP-FRET biosensor|| 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref>
|-
| Protease activity (Factor Xa) || ||1996 || 1 || <ref><pubmed>8707050</pubmed></ref>
|-
| Calpain activity ||pYSCS|| 2000 || 1 || <ref><pubmed>10688895</pubmed></ref>
|-
| Presenilin ||GFP-PSI-RFP|| 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref>
|-
|rowspan="5" | Other || Strain sensor ||stFRET|| 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref>
|-
| Membrane potential ||VSFP, Mermaid, ArcLight, VSFP-Butterfly|| 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref>
|-
| Myosin II ||GSldCB|| 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref>
|-
| HIV Rev protein ||YRGnC-11ad|| 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref>
|-
|| レドックス ||Redoxfluor, Gaskins|| 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
|}
 
The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.
 
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