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| (2人の利用者による、間の77版が非表示) |
| 1行目: |
1行目: |
| {| class="wikitable"
| | <ref name=Krapp1996><pubmed>8861960</pubmed></ref> |
| |+ 表1.
| | <ref name=Knoefler1996><pubmed>8703005</pubmed></ref> |
| |-
| | <ref name=Rose2001><pubmed>11562365</pubmed></ref> |
| | 分類||対象||プローブ名||年||プローブデザイン||参考文献
| | <ref name=Krapp1998><pubmed>9851981</pubmed></ref> |
| |-
| | <ref name=Kawaguchi2002><pubmed>12185368</pubmed></ref> |
| |rowspan="21" | 生体内小分子|| [[カルシウム]] ||Cameleon|| 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref>
| | <ref name=Sellick2004><pubmed>15543146</pubmed></ref> |
| |-
| | <ref name=Sellick2003><pubmed>14514650</pubmed></ref> |
| |[[サイクリックGMP]] ([[cGMP]]) ||CGY, Cygnet, pGES-DE2, cGi|| 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref>
| | <ref name=Hoveyda1999><pubmed>10507728</pubmed></ref> |
| |-
| | <ref name=Masui2008><pubmed>18606784</pubmed></ref> |
| |[[サイクリックAMP]] ([[cAMP]]) ||Epac|| 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref>
| | <ref name=Pan2013><pubmed>23325761</pubmed></ref> |
| |-
| | <ref name=Burlison2008><pubmed>18294628</pubmed></ref> |
| |[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) ||LIBRA, Fretino, FIRE|| 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref>
| | <ref name=AlShammari2011><pubmed>21749365</pubmed></ref> |
| |-
| | <ref name=Adell2000><pubmed>10768861</pubmed></ref> |
| |[[一酸化窒素]] ([[NO]]) ||NOA-1, Piccell|| 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref>
| | <ref name=Masui2007><pubmed>17938243</pubmed></ref> |
| |-
| | <ref name=Magnuson2013><pubmed>23823474</pubmed></ref> |
| |[[アデノシン3リン酸]] ([[ATP]]) ||A Team 1.03-nD/nA|| 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref>
| | <ref name=Fujitani2017><pubmed>28420858</pubmed></ref> |
| |-
| | <ref name=VeiteSchmahl2017><pubmed>28697176</pubmed></ref> |
| |[[エストロゲン]] ||SCCoR|| 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref>
| | <ref name=Hingorani2003><pubmed>14706336</pubmed></ref> |
| |-
| | <ref name=Obata2001><pubmed>11318877</pubmed></ref> |
| |[[アンドロゲン]] ||Ficaro|| 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref>
| | <ref name=Hoshino2005><pubmed>16039563</pubmed></ref> |
| |-
| | <ref name=Hoshino2006><pubmed>16997750</pubmed></ref> |
| |[[グルココルチコイド受容体]]リガンド ||GLUCOCOR|| 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref>
| | <ref name=Wullimann2011><pubmed>21559349</pubmed></ref> |
| |-
| | <ref name=Yamada2014><pubmed>24695699</pubmed></ref> |
| |[[神経成長因子]] ||ECaus|| 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref>
| | <ref name=Seto2014><pubmed>24535035</pubmed></ref> |
| |-
| | <ref name=Pascual2007><pubmed>17360405</pubmed></ref> |
| |[[核内受容体]] ||conpro|| 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref>
| | <ref name=Millen2008><pubmed>18513948</pubmed></ref> |
| |-
| | <ref name=Achim2014><pubmed>24196748</pubmed></ref> |
| |[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref>
| | <ref name=Lowenstein2023><pubmed>35262281</pubmed></ref> |
| |-
| | <ref name=BenArie1997><pubmed>9367153</pubmed></ref> |
| |[[ビタミンA]] ([[レチノイン酸]]) ||GEPRAS|| 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref>
| | <ref name=Machold2005><pubmed>16202705</pubmed></ref> |
| |-
| | <ref name=Wang2005><pubmed>16202707</pubmed></ref> |
| |[[wj:モリブデン酸|モリブデン酸]] ||MolyProbe|| 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref>
| | <ref name=Glasgow2005><pubmed>16291784</pubmed></ref> |
| |-
| | <ref name=Hori2012><pubmed>22830054</pubmed></ref> |
| |[[グルタミン酸]] ||FLIPE|| 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref>
| | <ref name=Fujitani2006><pubmed>17075007</pubmed></ref> |
| |-
| | <ref name=Nakhai2007><pubmed>17301087</pubmed></ref> |
| |[[wj:亜鉛|Zn<sup>2+</sup>]] ||eCALWY-1|| 2009 || 2 || <ref><pubmed>19718032</pubmed></ref>
| | <ref name=Dullin2007><pubmed>17910758</pubmed></ref> |
| |-
| | <ref name=Fujiyama2009><pubmed>19439493</pubmed></ref> |
| |[[wj:塩素|Cl<sup>-</sup>]] ||Clomeleon|| 2000 || other || <ref><pubmed>11055428</pubmed></ref>
| | <ref name=Yamada2007><pubmed>17928434</pubmed></ref> |
| |-
| | <ref name=Aldinger2008><pubmed>18184775</pubmed></ref> |
| |[[wj:水素イオン濃度|水素イオン濃度]] (pH) ||GFpH, YFpH|| 2001 || other || <ref><pubmed>11716495</pubmed></ref>
| | <ref name=Fujiyama2018><pubmed>29972793</pubmed></ref> |
| |-
| | <ref name=Horie2018><pubmed>30228204</pubmed></ref> |
| |[[wj:グルコース|グルコース]] ||FLIPglu|| 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref>
| | <ref name=Russ2015><pubmed>25878276</pubmed></ref> |
| |-
| | <ref name=Uhlen2015><pubmed>25613900</pubmed></ref> |
| |[[wj:マルトース|マルトース]]||FLIPmal|| 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref>
| | <ref name=Duque2022><pubmed>34125483</pubmed></ref> |
| |-
| | <ref name=Beres2006><pubmed>16354684</pubmed></ref> |
| |[[wj:リボース|リボース]]||FLIPrib|| 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref>
| | <ref name=Masui2010><pubmed>20398665</pubmed></ref> |
| |-
| | <ref name=Hori2008><pubmed>18198335</pubmed></ref> |
| |rowspan="26" | キナーゼ || [[カルシウム/カルモジュリン依存製タンパク質キナーゼII]] ([[CaMKII]]) ||Camui α, green-Camui α, Camk2a reporter|| 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref>
| | <ref name=Lelievre2011><pubmed>21839069</pubmed></ref> |
| |-
| | <ref name=Hanoun2014><pubmed>25355311</pubmed></ref> |
| | [[Src]] ||Srcus|| 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref>
| | <ref name=Rodolosse2009><pubmed>18834332</pubmed></ref> |
| |-
| | <ref name=Jin2019><pubmed>30470852</pubmed></ref> |
| | プロテインキナーゼC (PKC) ||CKAR, CY-PKCdelta|| 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref>
| | <ref name=Hanotel2014><pubmed>24370451</pubmed></ref> |
| |-
| | <ref name=Whittaker2021><pubmed>34730112</pubmed></ref> |
| | プロテインキナーゼD (PKD) ||DKAR|| 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref>
| | <ref name=Chang2013><pubmed>23639443</pubmed></ref> |
| |-
| | <ref name=Watanabe2015><pubmed>25995483</pubmed></ref> |
| | プロテインキナーゼA (PKA) ||ART, AKAR|| 2000, 2001 || 3-3 || <ref><pubmed>10700148</pubmed></ref><ref><pubmed>11752448</pubmed></ref>
| | <ref name=Jin2015><pubmed>25966682</pubmed></ref> |
| |- Table 1 A list of genetically encoded FRET probes.
| | <ref name=Nishida2010><pubmed>19887377</pubmed></ref> |
| | Abl ||Picchu|| 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
| | <ref name=Henke2009><pubmed>19641016</pubmed></ref> |
| |-
| | <ref name=Wiebe2007><pubmed>17403901</pubmed></ref> |
| | Bcr-Abl ||Bcr-Abl activity sensor||2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref>
| | <ref name=Meredith2013><pubmed>23754747</pubmed></ref> |
| |-
| | <ref name=Schaffer2010><pubmed>20627083</pubmed></ref> |
| | c-Raf ||Prin-cRaf|| 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref>
| | <ref name=AhnfeltRonne2012><pubmed>22096075</pubmed></ref> |
| |-
| | <ref name=Mona2016><pubmed>27350561</pubmed></ref> |
| | PAK1 ||Pakabi|| 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref>
| | <ref name=Meredith2009><pubmed>19741120</pubmed></ref> |
| |-
| | <ref name=Liu2013><pubmed>23652001</pubmed></ref> |
| | B-raf ||Prin-Braf|| 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref>
| | <ref name=Ito2023><pubmed>37248264</pubmed></ref> |
| |-
| | <ref name=Millen2014><pubmed>24733890</pubmed></ref> |
| | ZAP-70 ||ROZA|| 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref>
| | <ref name=Huang2008><pubmed>18634777</pubmed></ref> |
| |-
| | <ref name=Bikoff2016><pubmed>26949184</pubmed></ref> |
| | Akt ||Aktus, BKAR, Akind|| 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref><pubmed> 17407381</pubmed></ref>
| | <ref name=Zhang2017><pubmed>29045835</pubmed></ref> |
| |-
| | <ref name=Escalante2020><pubmed>33238109</pubmed></ref> |
| | ERK ||Miu2, Erkus, EKAR|| 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref>
| | <ref name=Jusuf2009><pubmed>19732413</pubmed></ref> |
| |-
| | <ref name=Jusuf2011><pubmed>21325522</pubmed></ref> |
| | インシュリン受容体 ||Phocus|| 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref>
| | <ref name=Mazurier2014><pubmed>24643195</pubmed></ref> |
| |-
| | <ref name=Bessodes2017><pubmed>28863786</pubmed></ref> |
| | 上皮成長因子受容体 (EGFR) || ||2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref>
| | <ref name=RazyKrajka2012><pubmed>22642675</pubmed></ref> |
| |-
| | <ref name=Maricich2009><pubmed>19741118</pubmed></ref> |
| | Ataxia telangiectasia mutated (ATM) || || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref>
| | <ref name=Bae2009><pubmed>19371731</pubmed></ref> |
| |-
| | <ref name=Elliott2023><pubmed>37055006</pubmed></ref> |
| |オーロラBキナーゼ || || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref>
| | <ref name=Iskusnykh2016><pubmed>26937009</pubmed></ref> |
| |-
| | <ref name=Kohl2012><pubmed>22539838</pubmed></ref> |
| | Cyclin B1-CDK1 || || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref>
| | <ref name=Fukuda2008><pubmed>18591390</pubmed></ref> |
| |-
| | <ref name=Sakikubo2018><pubmed>30361559</pubmed></ref> |
| | ミオシン軽鎖リン酸化酵素 ||MLCK-FIP || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref>
| |
| |-
| |
| | JNK ||JNKAR1, JUNKAR1EV || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref>
| |
| |-
| |
| | RSK ||Eevee-RSK|| 2011 || 3-3 || <ref name=ref21976697></ref>
| |
| |-
| |
| | S6K ||Eevee-S6K|| 2011 || 3-3 || <ref name=ref21976697></ref>
| |
| |-
| |
| | Focal Adhesion Kinase (FAK) ||CYFAK413, FERM-sensor|| 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref>
| |
| |-
| |
| | PLK1 || || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref>
| |
| |-
| |
| | SAP3K || || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref>
| |
| |-
| |
| | DAPK1 ||DAPK1(334)-F40|| 2011 || 3-1 || <ref><pubmed>21506563</pubmed></ref>
| |
| |-
| |
| | ホスファターゼ || カルシニューリン ||CaNAR1|| 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref>
| |
| |-
| |
| |rowspan="8" | 低分子量GTPアーゼ || Ras ||Raichu-Ras, Fras|| 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref>
| |
| |-
| |
| | Rap ||Raichu-Rap|| 2001 || 3-2 || <ref name=ref11429608></ref>
| |
| |-
| |
| | Rac ||Raichu-Rac1|| 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref>
| |
| |-
| |
| | Rab5 ||Raichu-Rab5|| 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref>
| |
| |-
| |
| | Rho ||Raichu-RhoA|| 2003, 2011 || 3-2, 2 || <ref><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref>
| |
| |-
| |
| | Cdc42 ||Raichu-cdc42|| 2004, 2011 || 3-2, 2 || <ref><pubmed>14570905</pubmed></ref><ref><pubmed> 21423166</pubmed></ref>
| |
| |-
| |
| | Ral ||Raichu-Ral|| 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref>
| |
| |-
| |
| | TC10 ||Raichu-TC10|| 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref>
| |
| |-
| |
| |rowspan="6" | シグナル伝達 || RCC1(GEF of Ran) ||CFP-RCC1-YFP|| 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref>
| |
| |-
| |
| | CrkII phosphorylation ||Picchu|| 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref>
| |
| |-
| |
| | N-WASP ||Stinger|| 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref>
| |
| |-
| |
| | アドレナリン受容体 ||α<sub>2A</sub>AR-cam|| 2003 || 3-1 || <ref name=ref12808462><pubmed>12808462</pubmed></ref>
| |
| |-
| |
| | Parathyroid hormone receptor ||PTHR-cam|| 2003 || 3-1 || <ref name=ref12808462></ref>
| |
| |-
| |
| | 細胞膜カルシウムポンプ ||BFP-PMCA-GFP|| 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref>
| |
| |-
| |
| | アセチル化 || ヒストンアセチル化 ||Histac|| 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref>
| |
| |-
| |
| |rowspan="6" | 脂質 || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) ||Fllip, FLIMPA|| 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref>
| |
| |-
| |
| | Phosphatidylinositol (4,5)-bisphosphate (PIP2) ||Pippi-PI(4,5)P<sub>2</sub>|| 2008 || 3-4 || <ref name=ref18685081><pubmed>18685081</pubmed></ref>
| |
| |-
| |
| | Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) ||Pippi-PI(3,4)P<sub>2</sub>|| 2008 || 3-4 || <ref name=ref18685081></ref>
| |
| |-
| |
| | Phosphatidylinositol 4-phosphate (PI4P) ||Pippi-PI(4)P|| 2008 || 3-4 || <ref name=ref18685081></ref>
| |
| |-
| |
| | ホスファチジン酸 ||Pii|| 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref>
| |
| |-
| |
| | ジアシルグリセロール (DAG) ||Daglas, DIGDA|| 2006, 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref><ref><pubmed> 16990811</pubmed></ref>
| |
| |-
| |
| |rowspan="6" | タンパク質相互作用 || アクチン || ||2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref>
| |
| |-
| |
| | PDK1-Akt interaction || ||2007 || 2 || <ref><pubmed>17407381</pubmed></ref>
| |
| |-
| |
| | Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction || || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref>
| |
| |-
| |
| | Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG || ||2010 || 2 || <ref><pubmed>20622991</pubmed></ref>
| |
| |-
| |
| | Cofiin-actin interaction || ||2008 || 2 || <ref><pubmed>17993279</pubmed></ref>
| |
| |-
| |
| | PTEN-Myosin V interaction || ||2009 || 2 || <ref><pubmed>19767745</pubmed></ref>
| |
| |-
| |
| |rowspan="8" | プロテアーゼ || カスパーゼ-3 ||EGFP-DEVD-EBFP|| 1998 || 1 || <ref><pubmed>9518501</pubmed></ref>
| |
| |-
| |
| | カスパーゼ-8 ||CFP-c3-YFP-c6-mRFP|| 2002 || 1 || <ref><pubmed>12409609</pubmed></ref>
| |
| |-
| |
| | カスパーゼ-9 ||SCAT9|| 2011 || 1 || <ref><pubmed>21637712</pubmed></ref>
| |
| |-
| |
| | カスパーゼ-7 ||VDEVDc|| 2006 || 1 || <ref><pubmed>17946841</pubmed></ref>
| |
| |-
| |
| | マトリックスメタロプロテアーゼ (MMP) ||YFP-MSS-CFP<sup>display</sup>, MTI-MMP-FRET biosensor|| 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref>
| |
| |-
| |
| | プロテアーゼ活性 (Factor Xa) || ||1996 || 1 || <ref><pubmed>8707050</pubmed></ref>
| |
| |-
| |
| |カルパイン活性||pYSCS|| 2000 || 1 || <ref><pubmed>10688895</pubmed></ref>
| |
| |-
| |
| | プレセニリン ||GFP-PSI-RFP|| 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref>
| |
| |-
| |
| |rowspan="5" | その他 || Strain sensor ||stFRET|| 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref>
| |
| |-
| |
| | 膜電位 ||VSFP, Mermaid, ArcLight, VSFP-Butterfly|| 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref>
| |
| |-
| |
| | ミオシン II ||GSldCB|| 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref>
| |
| |-
| |
| | ヒト免疫不全ウイルスRevタンパク質 ||YRGnC-11ad|| 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref>
| |
| |-
| |
| || レドックス ||Redoxfluor, Gaskins|| 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref>
| |
| |}
| |
| | |
| The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.
| |
| | |
| <references />
| |