「テンプレート:PBB/6722」の版間の差分

Serum response factor (c-fos serum response element-binding transcription factor)
	PDB rendering based on 1hbx.
Available structures
PDB	1HBX, 1K6O, 1SRS
Identifiers
Symbols	SRF; MCM1
External IDs	OMIM: 600589 MGI: 106658 HomoloGene: 31135 GeneCards: SRF Gene
Gene Ontology
Molecular function	• RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; • RNA polymerase II transcription factor binding transcription factor activity; • RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; • chromatin binding; • sequence-specific DNA binding transcription factor activity; • sequence-specific distal enhancer binding RNA polymerase II transcription factor activity; • protein binding; • transcription factor binding; • serum response element binding; • protein homodimerization activity; • sequence-specific DNA binding;
Cellular component	• nuclear chromatin; • nucleus; • nucleolus; • cytoplasm; • cytoplasm; • endoplasmic reticulum;
Biological process	• patterning of blood vessels; • in utero embryonic development; • mesoderm formation; • neuron migration; • trophectodermal cell differentiation; • heart looping; • morphogenesis of an epithelial sheet; • cell migration involved in sprouting angiogenesis; • leukocyte differentiation; • transcription from RNA polymerase II promoter; • actin filament organization; • cell-matrix adhesion; • multicellular organismal development; • gastrulation; • heart development; • long-term memory; • negative regulation of cell proliferation; • associative learning; • response to toxin; • response to hormone stimulus; • epithelial structure maintenance; • positive regulation of transcription via serum response element binding; • hippocampus development; • tangential migration from the subventricular zone to the olfactory bulb; • contractile actin filament bundle assembly; • regulation of cell adhesion; • platelet activation; • platelet formation; • negative regulation of cell migration; • neuron projection development; • regulation of water loss via skin; • response to cytokine stimulus; • response to cytokine stimulus; • megakaryocyte development; • dorsal aorta morphogenesis; • stress fiber assembly; • skin morphogenesis; • positive thymic T cell selection; • sarcomere organization; • positive regulation of cell differentiation; • positive regulation of transcription from RNA polymerase II promoter; • positive regulation of smooth muscle contraction; • muscle cell homeostasis; • developmental growth; • neuron development; • erythrocyte development; • regulation of smooth muscle cell differentiation; • positive regulation of filopodium assembly; • cardiac myofibril assembly; • angiogenesis involved in wound healing; • hemopoietic stem cell differentiation; • positive regulation of transcription initiation from RNA polymerase II promoter; • long term synaptic depression; • heart trabecula formation; • cardiac vascular smooth muscle cell differentiation; • eyelid development in camera-type eye; • tight junction assembly; • primitive streak formation; • epithelial cell-cell adhesion; • cellular senescence;
	Sources: Amigo / QuickGO
RNA expression pattern
	More reference expression data
Orthologs

2012年5月6日 (日) 23:45時点における版

@@ 1行目: / 1行目: @@
 {{GNF_Protein_box
   | Name = Serum response factor (c-fos serum response element-binding transcription factor)
-  | image = PBB_Protein_SRF_image.jpg
+  | image = SRF1.jpg
   | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1hbx.
   | PDB = {{PDB2|1HBX}}, {{PDB2|1K6O}}, {{PDB2|1SRS}}

「テンプレート:PBB/6722」の版間の差分

2012年5月6日 (日) 23:45時点における版

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