テンプレート:PBB/2932

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Glycogen synthase kinase 3 beta

PDB rendering based on 1gng.

Available structures
PDB	1GNG, 1H8F, 1I09, 1J1B, 1J1C, 1O9U, 1PYX, 1Q3D, 1Q3W, 1Q41, 1Q4L, 1Q5K, 1R0E, 1UV5, 2JDO, 2JDR, 2JLD, 2O5K, 2OW3, 2X39, 2XH5, 3CQU, 3CQW, 3DU8, 3E87, 3E88, 3E8D, 3F7Z, 3F88, 3GB2, 3I4B, 3L1S, 3M1S, 3PUP, 3Q3B, 3SAY, 3SD0, 3ZRK, 3ZRL, 3ZRM, 4ACC, 4ACD, 4ACG, 4ACH, 4AFJ, 4DIT, 4EKK

Identifiers

External IDs

OMIM: 605004 MGI: 1861437 HomoloGene: 55629 GeneCards: GSK3B Gene

2.7.11.26 2.7.11.1, 2.7.11.26

Gene Ontology
Molecular function	• RNA polymerase II transcription factor binding • p53 binding • protein serine/threonine kinase activity • protein serine/threonine kinase activity • protein binding • ATP binding • beta-catenin binding • kinase activity • kinase activity • protein kinase binding • ubiquitin protein ligase binding • protein kinase A catalytic subunit binding • tau-protein kinase activity • NF-kappaB binding
Cellular component	• nucleus • nucleolus • cytoplasm • centrosome • cytosol • plasma membrane • beta-catenin destruction complex • beta-catenin destruction complex • Axin-APC-beta-catenin-GSK3B complex
Biological process	• epithelial to mesenchymal transition • positive regulation of cell-matrix adhesion • glycogen metabolic process • protein phosphorylation • ER overload response • epidermal growth factor receptor signaling pathway • axon guidance • fibroblast growth factor receptor signaling pathway • phosphorylation • peptidyl-serine phosphorylation • hippocampus development • negative regulation of protein complex assembly • positive regulation of protein complex assembly • negative regulation of protein binding • positive regulation of Rac GTPase activity • regulation of microtubule-based process • intracellular signal transduction • negative regulation of apoptotic process • negative regulation of glycogen biosynthetic process • positive regulation of protein catabolic process • positive regulation of protein export from nucleus • nerve growth factor receptor signaling pathway • phosphatidylinositol-mediated signaling • negative regulation of NFAT protein import into nucleus • canonical Wnt receptor signaling pathway • canonical Wnt receptor signaling pathway • superior temporal gyrus development • negative regulation of canonical Wnt receptor signaling pathway • negative regulation of type B pancreatic cell development • negative regulation of glycogen (starch) synthase activity
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000082701

ENSMUSG00000022812

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 3:
119.54 – 119.81 Mb

Chr 16:
38.09 – 38.25 Mb

PubMed search

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