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| Gene (gene symbol) | Chromosomal localization | Precursor | Active ペプチド (s) | Mouse brain expression |
| Opioid gene family | ||||
| プロエンケファリン | PENK | プレプロエンケファリン | Leu-エンケファリン, Met-エンケファリン, アミドルフィン, アドレノルフィン, ペプチド B, ペプチドE, ペプチドF, BAM22P | Penk |
| Pro-opiomelanocortin gene (POMC) | POMC | POMC | a-メラノサイト-プレプロ ホルモン (a-MSH), g-メラノサイト-プレプロ ホルモン (g-MSH), ß-メラノサイト-プレプロ ホルモン (ß-MSH), adrenocorticotropic ホルモン (ACTH), ß-エンドルフィン, a-エンドルフィン, g-エンドルフィン, ß-lipoprotein (ß-LPH), g-lipoprotein (g-LPH), corticotropin-like intermediate ペプチド (CLIP) | Pomc |
| Pro-ダイノフィリン gene (PDYN) | PDYN | プレプロ-ダイノフィリン | ダイノフィリン A, ダイノフィリン B, a-neo-エンドルフィン, ß-neo-エンドルフィン, ダイノフィリン-32, leu-morphin | Pdyn |
| Orphanin gene, プレプロnociceptin gene (PNOC) | PNOC | プレプロ-nociceptin, プレプロ-orphanin | Nociceptin (orphanin FQ), neuroペプチド1, neuroペプチド 2 | Pnoc |
| Vasopressin/oxytocin gene family | ||||
| Vasopressin gene (AVP) | AVP | プレプロ-vasopressin-neurophysin II | Vasopressin (VP), neurophysin II (NP II), C-末端 glycoペプチド CPP | Avp |
| Oxytocin gene (OXT) | OXT | プレプロ-oxytocin-neurophysin I | Oxytocin (OT), neurophysin I (NP 1) | Oxt |
| CCK/gastrin gene family | ||||
| Gastrin gene (GAST) | GAST | プレプロ-gastrin | Gastrin-34, gastrin-17, gastrin-4 | Gast |
| Cholecystokinin gene (CCK) | CCK | プレプロ-CCK | CCK-8, CCK-33, CCK-58 | Cck |
| Somastostatin gene family | ||||
| Somastostatin gene (SST) | SST | プレプロ-somatostatin | SS-12, SS-14, SS-28, antrin | Sst |
| Cortistatin gene (CST) | 該当無し | プレプロ-cortistatin | cortistatin-29, cortistatin-17 | 該当無し |
| F- and Y-amide gene family | ||||
| Gonadotropin inhibitory ホルモン gene, RF-amide related ペプチド gene (RFRP) | 該当無し | プレプロ-NPRF | QRF-amide (neuroペプチド RF-amide, GnIH, p518, RF-related ペプチド-2), RF-related ペプチド-1, RF-related ペプチド-3 | 該当無し |
| Neuroペプチド FF gene (NPFF), | NPFF | プレプロ-NPFF | Neuroペプチド FF, neuroペプチド AF, neuroペプチド SF | Npff |
| Neuroペプチド Y gene (NPY) | NPY | プレプロ-NPY | NPY, C-flanking ペプチド CPON | Npy |
| Pancreatic polyペプチド gene (PPY) | PPY | プレプロ-PPY | PPY | Ppy |
| ペプチド YY gene (PYY) | PYY | プレプロ-PYY | PYY, PYY-(3-36) | Pyy |
| Prolactin-releasing ペプチド (PRLH) | PRLH | プレプロ-PrRP | PrRP-31, PrRP-20 | not available |
| Calcitonin gene family | ||||
| Calcitonin I gene (CALCA) | CALCA | プレプロ-CALC | Calcitonin, katacalcin | Calca |
| プレプロ-CGRP-alpha | Calcitonin gene related ペプチド I (a-CGRP) | |||
| Calcitonin II gene (CALCB) | CALCB | プレプロ-CGRP-beta | Calcitonin gene related ペプチド II (ß-CGRP) | Calcb |
| Islet amyloid polyペプチド gene (IAPP), Amylin gene | IAPP | プレプロ-IAPP | IAPP (amylin, amyloid polyペプチド) | Iapp |
| Adrenomedullin gene (ADM) | ADM | プレプロ-adrenomedullin | Adrenomedullin, AM, PAMP | Adm |
| Adrenomedullin-2 gene (ADM2) | ADM2 | プレプロ-adrenomedullin-2 | Adrenomedullin-2, intermedin-long (IMDL), intermedin-short(IMDS) | Adm2 |
| Natriuretic factor gene family | ||||
| Atrial natriuretic factor gene (NPPA) | NPPA | プレプロ-ANP | Atrial natriuretic factor (natriuretic ペプチド A, ANF, ANP, natriodilatine, cardiodilatine-related ペプチド) | 該当無し |
| Brain natriuretic factor gene (NPPB) | NPPB | プレプロ-BNP | Brain natriuretic factor (natriuretic ペプチド B, BNF, BNP) | Nppb |
| Natriuretic ペプチド precursor C gene (NPPC) | NPPC | プレプロ-CNP | C-type natriuretic ペプチド (CNP-23), CNP-29, CNP-53 | Nppc |
| Bombesin-like ペプチド gene family | ||||
| Gastrin releasing ペプチド gene (GRP) | GRP | prero-GRP-1 | GRP-27, GRP-14, GRP-10 (neuromedin C) | Grp |
| プレプロ-GRP-2 | GRP-27, GRP-14, GRP-10(neuromedin C) | |||
| プレプロ-GRP-3 | GRP-27, GRP-14, GRP-10 (neuromedin C) | |||
| Neuromedin B gene (NMB) | NMB | プレプロ-neuromedin B1 | Neuromedin B (Ranatensin-like ペプチド, RLP) | Nmb |
| プレプロ-neuromedin B2 | Neuromedin B (Ranatensin-like ペプチド, RLP) | |||
| Endothelin gene family | ||||
| Endothelin 1 gene (EDN1) | EDN1 | プレプロ-endothelin 1 (PPET1) | Endothelin 1 (ET-1) | Edn1 |
| Endothelin 2 gene (EDN2) | EDN2 | プレプロ-endothelin 2 (PPET2)2 | Endothelin 2 (ET-2) | Edn2 |
| Endothelin 3 gene (EDN3) | EDN3 | プレプロ-endothelin 3 (PPET3) | Endothelin 3 (ET-3) | Edn3 |
| Glucagon/secretin gene family | ||||
| Glucagon gene (CGC) | 該当無し | プレプロ-glucagon | Glicentin; Glicentin-related polyペプチド (GRPP); Oxyntomodulin (OXY) (OXM); Glucagon; Glucagon-like ペプチド 1 (GLP-1); Glucagon-like ペプチド 1(7-37) (GLP-1(7-37));
Glucagon-like ペプチド 1(7-36) (GLP-1(7-36)); Glucagon-like ペプチド 2 (GLP-2) ||該当無し | |
| Secretin gene (SCT) | SCT | プレプロ-secretin | secretin | Sct |
| Vasoactive intestinal ペプチド gene (VIP) | VIP | プレプロ-VIP-1 | VIP, PHM-27/PHI-27, PHV-42 | Vip |
| プレプロ-VIP-2 | VIP, PHM-27/PHI-27, PHV-42 | |||
| Pituitary adenylcyclase-activated ペプチド gene (ADCYAP1) | ADCYAP1 | プレプロ-PACAP | PACAP-38, PACAP-27, PRP-48 | Adcyap1 |
| Growth ホルモン releasing ホルモン gene (GHRH) | GHRH | プレプロ-GHRH | GHRH (somatoliberin,GRF, somatocrinin, somatorelin, sermorelin) | Ghrh |
| Gastric inhibitory ペプチド gene (GIP) | GIP | プレプロ-GIP | GIP (gastric inhibitory ペプチド, glucose-dependent insulinotropic polyペプチド) | Gip |
| CRH-related gene family | ||||
| Corticotropin-releasing ホルモン gene (CRH) | CRH | プレプロ-CRH | CRH | Crh |
| Urocortin gene (UCN) | UCN | プレプロ-UNC I | UNC I | Ucn |
| Urocortin II gene (UCN2) | UCN2 | プレプロ-UNC II | UNC II, stresscopin-related ペプチド | not available |
| Urocortin III gene (UCN3) | UCN3 | プレプロ-UNC III | UNC III, stresscopin | Ucn3 |
| Urotensin-II (UTS2) | UTS2 | プレプロ-urotensin-2, isoform a | Urotensin-2 | not available |
| プレプロ-urotensin-2, isofrom b | Urotensin-2 | |||
| Urotensin-II domain containing (UTS2D) | 該当無し | プレプロ-urotensin-2B | Urotensin-2-related ペプチド,urotensin-2B | Uts2d |
| Kinin and tensin gene family | ||||
| プレプロtachykinin A gene (TAC1) | TAC1 | a-PPTA | Substance P, neurokinin A (NKA, substance K, neuromedin L), neuroペプチド K, neuroペプチド gamma | Tac1 |
| ß-PPTA | Substance P, neuroペプチド K, neurokinin A | |||
| g-PPTA | Substance P, neurokinin A, neuroペプチド g | |||
| δ-PPTA | Substance P, neuroペプチド K, neurokinin A | |||
| プレプロtachykinin B gene (TAC3) | TAC3 | PPTB, isoform 1 | Neuromedin K, neurokinin B | Tac3 |
| PPTB, isoform 2 | Neuromedin K, neurokinin B | |||
| Neuromedins | ||||
| Neuromedin S gene (NMS) | NMS | プレプロ-neuromedin S | Neuromedin S | not available |
| Neuromedin U gene (NMU) | NMU | プレプロ-neuromedin U, multiple isoforms | Neuromedin U | Nmu |
| Tensins and Kinins | ||||
| Kininogen-1 gene (KNG1) | KNG1 | Kininogen-1 precursor, multiple isoforms | Bradykinin, kallidin, LMW-K-kinin, HMW-K-kinin | Kng1 |
| Angiotensin gene (AGT) | AGT | Angiotensinogen プレプロtein | Angiotensin I, angiotensin II, angiotensin-(1–7) | Agt |
| Neurotensin gene (NTS) | NTS | プレプロ-neurotensin | Neurotensin (NT), neuromedin N | Nts |
| Granins | ||||
| Chromogranin A gene (CHGA) | CHGA | Chromogranin A precursor | Chromogranin A, beta-granin, vasostatin | Chga |
| Chromogranin B gene (CHGB) | CHGB | Chromogranin B precursor | Chromogranin B (secretogranin I), CCB ペプチド, GAWK ペプチド | Chgb |
| Chromogranin B precursor variant | Chromogranin B (secretogranin I) | |||
| Secretogranin II gene (SCG2) | SCG2 | Secretogranin II precursor , chromogranin C precurosor | Secretogranin II(chromogranin C), EM66, secretoneurin | Scg2 |
| Secretogranin III gene (SCG3) | SCG3 | Secretogranin III precursor | Secretogranin III | Scg3 |
| Secretory granule neuroendocrine protein 1, 7B2 gene (SGNE1) | 該当無し | Secretory granule neuroendocrine precursor | Secretory granule neuroendocrine protein-1 (7B2, secretogranain 5) | Sgne1 |
| VGF nerve growth factor inducible protein (VGF) | VGF | VGF-precursor | VGF (NGF-inducible protein, neurosectretory protein), TLPQ-62, TLPQ-21, AQEE-30, LQEQ-19 | Vgf |
| Motilin family | ||||
| Motilin gene (MLN) | MLN | プレプロ-motilin isoform 1 | motilin | not available |
| プレプロ-motilin isofrom 2 | Motilin, motillin-associated ペプチド | |||
| Ghrelin gene (GHRL) | GHRL | プレプロ-ghrelin | Ghrelin, obestatin | Ghrl |
| Galanin family | ||||
| Galanin gene (GAL) | GAL | プレプロ-galanin | Galanin, galanin message associated ペプチド (GMAP) | Gal |
| Galanin-like ペプチド precursor gene (GALP) | GALP | Galanin-like ペプチド precursor | Galanin-like ペプチド (GALP) | Galp |
| GnRH family | ||||
| Gonadotropin-releasing ホルモン gene (GnRH1) | GnRH1 | プレプロ-GnRH1 | GnRH (LHRH, gonadoliberin) | Gnrh1 |
| Gonadotropin-releasing ホルモン gene (GnRH2) | GnRH2 | プレプロ-GNRH2, Isoform-a | GnRH2 (LHRH II, gonadoliberin II) | not in mouse |
| プレプロ-GNRH2, Isoform-b | GnRH2 (LHRH II, gonadoliberin II) | not in mouse | ||
| プレプロ-GNRH2, Isoform-c | GnRH2 (LHRH II, gonadoliberin II) | not in mouse | ||
| Neuroペプチド B/W family | ||||
| Neuroペプチド B gene (NPB) | NPB | プレプロ-neuroペプチド B, PPL7 | Neuroペプチド B-23 (ペプチド L7), neuroペプチド B-29, | Npb |
| Neuroペプチド W gene (NPW) | NPW | プレプロ-neuroペプチド W, PPL8 | Neuroペプチド W-23 (ペプチド L8), neuroペプチド W-30, | Npw |
| Neuroペプチドs S gene (NPS) | NPS | プレプロ-neuroペプチド S | Neuroペプチド S | not available |
| Neurexophilins | ||||
| Neurexophilin-1 (NXPH1) | NXPH1 | Neurexophilin-1 precursor | Neurexophilin-1 | MXPH1 |
| Neurexophilin-2 (NXPH2) | NXPH2 | Neurexophilin-2 precursor | Neurexophilin-2 | MXPH2 |
| Neurexophilin-3 (NXPH3) | NXPH3 | Neurexophilin-3 precursor | Neurexophilin-3 | MXPH3 |
| Neurexophilin-4 (NXPH4) | NXPH4 | Neurexophilin-4 precursor | Neurexophilin-4 | Nxph4 |
| Insulin family | ||||
| Insulin gene (INS) | INS | プレプロ-insulin | insulin | |
| IGF-1 gene (IGF1) | IGF1 | IGF-1 precursor | IGF-1 (somatomedin C) | Igf1 |
| IGF-2 gene (IGF2) | IGF2 | IGF-2 precursor | IGF-2 (somatomedin A) | Igf2 |
| Relaxin-1 gene (RLN1) | RLN1 | プレプロ-relaxin-1 | Relaxin-1 | Rln1 |
| Relaxin-2 gene (RLN2) | RLN2 | プレプロ-relaxin-2, isoform 1 | Relaxin-2 | not in mouse |
| プレプロ-relaxin-2, Isoform 2 | Relaxin-2 | |||
| Relaxin-3 gene (RLN3) | RLN3 | プレプロ-relaxin-3 | Relaxin-3 | Rln3 |
| No-family neuroペプチドs | ||||
| Thyrotropin-releasing ホルモン gene (TRH) | TRH | プレプロ-TRH | TRH (thyroliberin) | Trh |
| Parathyroid ホルモン-like ホルモン gene (PTHLH) | PTHLH | プレプロ-PTH-like ホルモン, isoform 1 | PTHrP-(1-36), PTHrP-(38-94), PTHrP-(107-139) (osteostatin) | Pthlh |
| Melanin-concentrating ホルモン gene (PMCH) | PMCH | プレプロ-MCH | MCH, neuroペプチド Glu-Ile (NEI), neuroペプチド Gly-Glu (NGE) | not available |
| Hypocretin gene (HCRT) | HCRT | プレプロ-hypocretin | Hypocretin-1 (orexin A), hypocretin-2 (orexin B) | Hcrt |
| Cocaine- and amphetamine-regulated transcript gene (CART) | 該当無し | プレプロ-CART | CART-(1-39), CART-(42-89) | 該当無し |
| Agouti-related protein homolog gene (AGRP) | AGRP | AGRP precursor isoform 1 | AGRP | Agrp |
| プレプロ-AGRP isoform 2 | AGRP | |||
| Prolactin (PRL) | PRL | Prolactin precursor | Prolactin | Prl |
| Apelin gene (APLN) | APLN | プレプロ-apelin | Apelin-13, apelin-17, apelin-36 (APJ ligand, AGTRL1 ligand) | Apln |
| Metastasis-suppressor KiSS (KISS1) | KISS1 | Kiss-1 | Metastin (kisspeptin-54), (golgi transport 1 homolog A, golt1a), kisspeptin-14, kisspeptin-13, kisspeptin-10, | Kiss1 |
| Diazepam-binding inhibitor (DBI) | DBI | DBI isoform 1 | Diazepam-binding inhibitory ペプチド | Dbi |
| DBI isoform 2 | Diazepam-binding inhibitory ペプチド | |||
| DBI isoform 3 | Diazepam-binding inhibitory ペプチド | |||
| Cerebellins | ||||
| Cerebellin-1 gene (CBLN1) | CBLN1 | Cerebellin-1 precursor | Cerebellin-1 (Cbln1) | not available |
| Cerebellin-2 gene (CBLN2) | CBLN2 | Cerebellin-2-precursor | Cerebellin-2 (Cbln2) | Cbln2 |
| Cerebellin-3 gene (CBLN3) | CBLN3 | Cerebellin-3 precursor | Cerebellin-3 (Cbln3) | Cbln3 |
| Cerebellin-4 gene (CBLN4), | CBLN4 | Cerebellin-4 precursor | Cerebellin-4 (Cbln4, cerebellin-like glycoprotein-1) | Cbln4 |
| Adipose neuroeペプチドs | ||||
| Leptin/ob gene (LEP) | LEP | プレプロ-leptin | Leptin (obesin) | Lep |
| Adiponectin gene (ADIPOQ) | ADIPOQ | Adiponectin precursor | Adiponectin (Acpr30, adipocyte complement related protein; adipocyte, C1Q and collagen domain containing) | Adipoq |
| Visfatin gene (PBEF1) | 該当無し | Visfatin precursor | Visfatin-1 (pre-B cell colony enhancing factor-1 (PBEF1), nicotinamide phosphoribosyltransferase) | 該当無し |
| Resistin gene (RETN) | RETN | Resistin precursor | Resistin (Cysteine-rich secreted protein FIZZ3, Adipose tissue-specific secretory factor, Cysteine-rich secreted protein A12-alpha-like 2, ADSF, Xcp4) | Retn |
| Resistin-delta2 precursor | Resistin-delta2 | |||
| Resistin-like alpha gene (RETLA) | not in human | Resistin-like molecule alpha precursor (RELMalpha) | Resistin-like molecule alpha (found in inflammatory zone 1; FIZZ1, hypoxia-induced mitogenic factor, Xcp2). | 該当なし |
| Resistin-like beta gene (RETLB) | 該当無し | Resistin-like molecule beta precursor (RELMbeta) | Resistin-like molecule beta (Cysteine-rich secreted protein FIZZ2, Colon and small intestine-specific cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 1, Colon carcinoma-related gene protein, Xcp3). | not available |
| Resistin-like ggammane (RETLG) | not in human | Resistin-like molecule gamma precursor (RELMgamma) | Resistin-like molecule gamma (Cysteine-rich secreted protein FIZZ3, Xcp1) | 該当なし |
| Nucleobindin-2/NEFA gene (NUCB2) | NUCB2 | Nucleobindin-2 | Nesfatin-1 | Nucb2 |
| Ubiquitin-like 5 (UBL5) | UBL5 | Beacon precursor | Beacon | Ubl5 |