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|+ 表1. | |+ 表1. | ||
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| 分類||対象||年||プローブデザイン||参考文献 | | 分類||対象||プローブ名||年||プローブデザイン||参考文献 | ||
|- | |- | ||
|rowspan="21" | 生体内小分子|| [[カルシウム]] || 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref> | |rowspan="21" | 生体内小分子|| [[カルシウム]] ||Cameleon|| 1997 || 3-2 || <ref><pubmed>9278050</pubmed></ref> | ||
|- | |- | ||
|[[サイクリックGMP]] ([[cGMP]]) || 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref> | |[[サイクリックGMP]] ([[cGMP]]) ||CGY, Cygnet, pGES-DE2, cGi|| 2000, 2001, 2006 || 3-1 || <ref><pubmed>11140757</pubmed></ref><ref><pubmed>11226257</pubmed></ref><ref><pubmed>16369548</pubmed></ref> | ||
|- | |- | ||
|[[サイクリックAMP]] ([[cAMP]]) || 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref> | |[[サイクリックAMP]] ([[cAMP]]) ||Epac|| 2000,2004 || 2, 3-1 || <ref><pubmed>11872839</pubmed></ref><ref><pubmed> 15231839</pubmed></ref> | ||
|- | |- | ||
|[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) || 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref> | |[[イノシトール3リン酸]] ([[IP3|IP<sub>3</sub>]]) ||LIBRA, Fretino, FIRE|| 2004, 2005, 2006 || 3-1 || <ref><pubmed>15272011</pubmed></ref><ref><pubmed> 16053285</pubmed></ref><ref><pubmed> 16754959</pubmed></ref> | ||
|- | |- | ||
|[[一酸化窒素]] ([[NO]]) || 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref> | |[[一酸化窒素]] ([[NO]]) ||NOA-1, Piccell|| 2005, 2006 || 3-1 || <ref><pubmed>16176986</pubmed></ref><ref><pubmed> 17165805</pubmed></ref> | ||
|- | |- | ||
|[[アデノシン3リン酸]] ([[ATP]]) || 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref> | |[[アデノシン3リン酸]] ([[ATP]]) ||A Team 1.03-nD/nA|| 2012 || 3-1 || <ref><pubmed>19720993</pubmed></ref> | ||
|- | |- | ||
|[[エストロゲン]] || 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref> | |[[エストロゲン]] ||SCCoR|| 2004 || 3-3 || <ref><pubmed>15080726</pubmed></ref> | ||
|- | |- | ||
|[[アンドロゲン]] || 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref> | |[[アンドロゲン]] ||Ficaro|| 2006 || 3-3 || <ref><pubmed>16555356</pubmed></ref> | ||
|- | |- | ||
|[[グルココルチコイド受容体]]リガンド || 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref> | |[[グルココルチコイド受容体]]リガンド ||GLUCOCOR|| 2007 || 3-3 || <ref><pubmed>17897691</pubmed></ref> | ||
|- | |- | ||
|[[神経成長因子]] || 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref> | |[[神経成長因子]] ||ECaus|| 2008 || 3-3 || <ref><pubmed>18510313</pubmed></ref> | ||
|- | |- | ||
|[[核内受容体]] || 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref> | |[[核内受容体]] ||conpro|| 2007 || 3-2 || <ref><pubmed>17387660</pubmed></ref> | ||
|- | |- | ||
|[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref> | |[[O-N-アセチルグルコサミン]] ([[O-GlcNAc]]) || || 2006 || 3-3 || <ref><pubmed>17105262</pubmed></ref> | ||
|- | |- | ||
|[[ビタミンA]] ([[レチノイン酸]]) || 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref> | |[[ビタミンA]] ([[レチノイン酸]]) ||GEPRAS|| 2013 || 3-1 || <ref><pubmed>23563268</pubmed></ref> | ||
|- | |- | ||
|[[wj:モリブデン酸|モリブデン酸]] || 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref> | |[[wj:モリブデン酸|モリブデン酸]] ||MolyProbe|| 2013 || 3-1 || <ref><pubmed>23472155</pubmed></ref> | ||
|- | |- | ||
|[[グルタミン酸]] || 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref> | |[[グルタミン酸]] ||FLIPE|| 2005 || 3-1 || <ref><pubmed>15939876</pubmed></ref> | ||
|- | |- | ||
|[[wj:亜鉛|Zn<sup>2+</sup>]] || 2009 || 2 || <ref><pubmed>19718032</pubmed></ref> | |[[wj:亜鉛|Zn<sup>2+</sup>]] ||eCALWY-1|| 2009 || 2 || <ref><pubmed>19718032</pubmed></ref> | ||
|- | |- | ||
|[[wj:塩素|Cl<sup>-</sup>]] || 2000 || other || <ref><pubmed>11055428</pubmed></ref> | |[[wj:塩素|Cl<sup>-</sup>]] ||Clomeleon|| 2000 || other || <ref><pubmed>11055428</pubmed></ref> | ||
|- | |- | ||
|[[wj:水素イオン濃度|水素イオン濃度]] (pH) || 2001 || other || <ref><pubmed>11716495</pubmed></ref> | |[[wj:水素イオン濃度|水素イオン濃度]] (pH) ||GFpH, YFpH|| 2001 || other || <ref><pubmed>11716495</pubmed></ref> | ||
|- | |- | ||
|[[wj:グルコース|グルコース]] || 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref> | |[[wj:グルコース|グルコース]] ||FLIPglu|| 2003 || 3-1 || <ref><pubmed>12649277</pubmed></ref> | ||
|- | |- | ||
|[[wj:マルトース|マルトース]]|| 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref> | |[[wj:マルトース|マルトース]]||FLIPmal|| 2002 || 3-1 || <ref><pubmed>12097642</pubmed></ref> | ||
|- | |- | ||
|[[wj:リボース|リボース]]|| 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref> | |[[wj:リボース|リボース]]||FLIPrib|| 2003 || 3-1 || <ref><pubmed>14550551</pubmed></ref> | ||
|- | |- | ||
| Kinase || [[カルシウム/カルモジュリン依存製タンパク質キナーゼII]] ([[CaMKII]]) || 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref> | | Kinase || [[カルシウム/カルモジュリン依存製タンパク質キナーゼII]] ([[CaMKII]]) ||Camui α, green-Camui α, Camk2a reporter|| 2005, 2009, 2011, 2013 || 3-1 || <ref><pubmed>15788767</pubmed></ref><ref><pubmed> 19295602</pubmed></ref><ref><pubmed> 23602566</pubmed></ref><ref><pubmed> 21506563</pubmed></ref> | ||
|- | |- | ||
| Kinase || [[Src]] || 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref> | | Kinase || [[Src]] ||Srcus|| 2005, 2005, 2007 || 3-3 || <ref><pubmed>11752449</pubmed></ref><ref><pubmed> 15846350</pubmed></ref><ref><pubmed> 17284441</pubmed></ref> | ||
|- | |- | ||
| Kinase || Protein kinase C (PKC) || 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref> | | Kinase || Protein kinase C (PKC) ||CKAR, CY-PKCdelta|| 2003, 2005 || 3-3, 3-1 || <ref><pubmed>12782683</pubmed></ref><ref><pubmed> 15611119</pubmed></ref> | ||
|- | |- | ||
| Kinase || Protein kinase D (PKD) || 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref> | | Kinase || Protein kinase D (PKD) ||DKAR|| 2007 || 3-3 || <ref><pubmed>17189263</pubmed></ref> | ||
|- | |- | ||
| Kinase || Protein kinase A (PKA) || 2000, 2001 || 3-3 || <ref><pubmed>10700148</pubmed></ref><ref><pubmed>11752448</pubmed></ref> | | Kinase || Protein kinase A (PKA) ||ART, AKAR|| 2000, 2001 || 3-3 || <ref><pubmed>10700148</pubmed></ref><ref><pubmed>11752448</pubmed></ref> | ||
|- Table 1 A list of genetically encoded FRET probes. | |- Table 1 A list of genetically encoded FRET probes. | ||
| Kinase || Abl || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref> | | Kinase || Abl ||Picchu|| 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref> | ||
|- | |- | ||
| Kinase || Bcr-Abl || 2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref> | | Kinase || Bcr-Abl ||Bcr-Abl activity sensor||2010 || 3-3 || <ref><pubmed>20817824</pubmed></ref> | ||
|- | |- | ||
| Kinase || c-Raf || 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref> | | Kinase || c-Raf ||Prin-cRaf|| 2005 || 3-1 || <ref><pubmed>15711535</pubmed></ref> | ||
|- | |- | ||
| Kinase || PAK1 || 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref> | | Kinase || PAK1 ||Pakabi|| 2009 || 3-1 || <ref><pubmed>19574218</pubmed></ref> | ||
|- | |- | ||
| Kinase || B-raf || 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref> | | Kinase || B-raf ||Prin-Braf|| 2006 || 3-1 || <ref><pubmed>16858395</pubmed></ref> | ||
|- | |- | ||
| Kinase || ZAP-70 || 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref> | | Kinase || ZAP-70 ||ROZA|| 2008 || 3-3 || <ref><pubmed>18231606</pubmed></ref> | ||
|- | |- | ||
| Kinase || Akt || 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref><pubmed> 17407381</pubmed></ref> | | Kinase || Akt ||Aktus, BKAR, Akind|| 2003, 2005, 2007 || 3-3 || <ref><pubmed>12773546</pubmed></ref><ref><pubmed> 15583002</pubmed></ref><ref><pubmed> 17407381</pubmed></ref> | ||
|- | |- | ||
| Kinase || ERK || 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref> | | Kinase || ERK ||Miu2, Erkus, EKAR|| 2006, 2007, 2008 || 3-1,3-3,3-3 || <ref><pubmed>16418172</pubmed></ref><ref><pubmed> 17261026</pubmed></ref><ref><pubmed> 19033456</pubmed></ref> | ||
|- | |- | ||
| Kinase || Insulin receptor || 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref> | | Kinase || Insulin receptor ||Phocus|| 2002 || 3-3 || <ref><pubmed>11875431</pubmed></ref> | ||
|- | |- | ||
| Kinase || Epidermal Growth factor receptor (EGFR) || 2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref> | | Kinase || Epidermal Growth factor receptor (EGFR) || ||2001 || 3-3 || <ref><pubmed>11752449</pubmed></ref> | ||
|- | |- | ||
| Kinase || Ataxia telangiectasia mutated (ATM) || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref> | | Kinase || Ataxia telangiectasia mutated (ATM) || || 2007 || 3-3 || <ref><pubmed>17428747</pubmed></ref> | ||
|- | |- | ||
| Kinase || Aurora B kinase || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref> | | Kinase || Aurora B kinase || || 2008 || 3-3 || <ref><pubmed>18463638</pubmed></ref> | ||
|- | |- | ||
| Kinase || Cyclin B1-CDK1 || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref> | | Kinase || Cyclin B1-CDK1 || || 2010 || 3-3 || <ref><pubmed>20412769</pubmed></ref> | ||
|- | |- | ||
| Kinase || Myosine light chain kinase || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref> | | Kinase || Myosine light chain kinase ||MLCK-FIP || 2002 || 3-1 || <ref><pubmed>11815633</pubmed></ref> | ||
|- | |- | ||
| Kinase || JNK || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref> | | Kinase || JNK ||JNKAR1, JUNKAR1EV || 2010, 2011 || 3-3 || <ref><pubmed>20212108</pubmed></ref><ref name=ref21976697><pubmed> 21976697</pubmed></ref> | ||
|- | |- | ||
| Kinase || RSK || 2011 || 3-3 || <ref name=ref21976697></ref> | | Kinase || RSK ||Eevee-RSK|| 2011 || 3-3 || <ref name=ref21976697></ref> | ||
|- | |- | ||
| Kinase || S6K || 2011 || 3-3 || <ref name=ref21976697></ref> | | Kinase || S6K ||Eevee-S6K|| 2011 || 3-3 || <ref name=ref21976697></ref> | ||
|- | |- | ||
| Kinase || Focal Adhesion Kinase (FAK) || 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref> | | Kinase || Focal Adhesion Kinase (FAK) ||CYFAK413, FERM-sensor|| 2008, 2009 || 2, 3-1 || <ref><pubmed>17967873</pubmed></ref><ref><pubmed> 19208768</pubmed></ref> | ||
|- | |- | ||
| Kinase || PLK1 || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref> | | Kinase || PLK1 || || 2008 || 3-3 || <ref><pubmed>18615013</pubmed></ref> | ||
|- | |- | ||
| Kinase || SAP3K || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref> | | Kinase || SAP3K || || 2009 || 3-3 || <ref><pubmed>19737916</pubmed></ref> | ||
|- | |- | ||
| Kinase || DAPK1 || 2011 || 3-1 || <ref><pubmed>21506563</pubmed></ref> | | Kinase || DAPK1 ||DAPK1(334)-F40|| 2011 || 3-1 || <ref><pubmed>21506563</pubmed></ref> | ||
|- | |- | ||
| Phosphatase || Calcineurin || 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref> | | Phosphatase || Calcineurin ||CaNAR1|| 2008, 2013 || 3-1 || <ref><pubmed>23602566</pubmed></ref><ref><pubmed> 18493642</pubmed></ref> | ||
|- | |- | ||
| Small GTPase || Ras || 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref> | | Small GTPase || Ras ||Raichu-Ras, Fras|| 2001, 2006 || 3-2,2 || <ref><pubmed>16429133</pubmed></ref><ref name=ref11429608><pubmed> 11429608</pubmed></ref> | ||
|- | |- | ||
| Small GTPase || Rap || 2001 || 3-2 || <ref name=ref11429608></ref> | | Small GTPase || Rap ||Raichu-Rap|| 2001 || 3-2 || <ref name=ref11429608></ref> | ||
|- | |- | ||
| Small GTPase || Rac || 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref> | | Small GTPase || Rac ||Raichu-Rac1|| 2004 || 3-2 || <ref><pubmed>14570905</pubmed></ref> | ||
|- | |- | ||
| Small GTPase || Rab5 || 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref> | | Small GTPase || Rab5 ||Raichu-Rab5|| 2008 || 3-2 || <ref><pubmed>18385674</pubmed></ref> | ||
|- | |- | ||
| Small GTPase || Rho || 2003, 2011 || 3-2, 2 || <ref><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref> | | Small GTPase || Rho ||Raichu-RhoA|| 2003, 2011 || 3-2, 2 || <ref><pubmed>21423166</pubmed></ref><ref><pubmed> 12860967</pubmed></ref> | ||
|- | |- | ||
| Small GTPase || Cdc42 || 2004, 2011 || 3-2, 2 || <ref><pubmed>14570905</pubmed></ref><ref><pubmed> 21423166</pubmed></ref> | | Small GTPase || Cdc42 ||Raichu-cdc42|| 2004, 2011 || 3-2, 2 || <ref><pubmed>14570905</pubmed></ref><ref><pubmed> 21423166</pubmed></ref> | ||
|- | |- | ||
| Small GTPase || Ral || 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref> | | Small GTPase || Ral ||Raichu-Ral|| 2004 || 3-3 || <ref><pubmed>15034142</pubmed></ref> | ||
|- | |- | ||
| Small GTPase || TC10 || 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref> | | Small GTPase || TC10 ||Raichu-TC10|| 2006 || 3-2 || <ref><pubmed>16950130</pubmed></ref> | ||
|- | |- | ||
| Signal transduction || RCC1(GEF of Ran) || 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref> | | Signal transduction || RCC1(GEF of Ran) ||CFP-RCC1-YFP|| 2008 || 3-1 || <ref><pubmed>18762580</pubmed></ref> | ||
|- | |- | ||
| Signal transduction || CrkII phosphorylation || 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref> | | Signal transduction || CrkII phosphorylation ||Picchu|| 2001 || 3-1 || <ref><pubmed>11406630</pubmed></ref> | ||
|- | |- | ||
| Signal transduction || N-WASP || 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref> | | Signal transduction || N-WASP ||Stinger|| 2004 || 3-1 || <ref><pubmed>15084285</pubmed></ref><ref><pubmed> 14732696</pubmed></ref> | ||
|- | |- | ||
| Signal transduction || Adrenergic receptor || 2003 || 3-1 || <ref name=ref12808462><pubmed>12808462</pubmed></ref> | | Signal transduction || Adrenergic receptor ||α2AAR-cam|| 2003 || 3-1 || <ref name=ref12808462><pubmed>12808462</pubmed></ref> | ||
|- | |- | ||
| Signal transduction || Parathyroid hormone receptor || 2003 || 3-1 || <ref name=ref12808462></ref> | | Signal transduction || Parathyroid hormone receptor ||PTHR-cam|| 2003 || 3-1 || <ref name=ref12808462></ref> | ||
|- | |- | ||
| Signal transduction || Plasma membrane Calcium pump || 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref> | | Signal transduction || Plasma membrane Calcium pump ||BFP-PMCA-GFP|| 2007 || 3-1 || <ref><pubmed>17901055</pubmed></ref> | ||
|- | |- | ||
| Acetylation || Histone acetylation || 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref> | | Acetylation || Histone acetylation ||Histac|| 2004, 2009 || 3-3 || <ref><pubmed>15137760</pubmed></ref><ref><pubmed> 19805290</pubmed></ref> | ||
|- | |- | ||
| Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) || 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref> | | Lipid || Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) ||Fllip, FLIMPA|| 2003 || 3-4 || <ref><pubmed>14528311</pubmed></ref> | ||
|- | |- | ||
| Lipid || Phosphatidylinositol (4,5)-bisphosphate (PIP2) || 2008 || 3-4 || <ref name=ref18685081><pubmed>18685081</pubmed></ref> | | Lipid || Phosphatidylinositol (4,5)-bisphosphate (PIP2) ||Pippi-PI(4,5)P2|| 2008 || 3-4 || <ref name=ref18685081><pubmed>18685081</pubmed></ref> | ||
|- | |- | ||
| Lipid || Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) || 2008 || 3-4 || <ref name=ref18685081></ref> | | Lipid || Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) ||Pippi-PI(3,4)P2|| 2008 || 3-4 || <ref name=ref18685081></ref> | ||
|- | |- | ||
| Lipid || Phosphatidylinositol 4-phosphate (PI4P) || 2008 || 3-4 || <ref name=ref18685081></ref> | | Lipid || Phosphatidylinositol 4-phosphate (PI4P) ||Pippi-PI(4)P|| 2008 || 3-4 || <ref name=ref18685081></ref> | ||
|- | |- | ||
| Lipid || Phosphatidic acid || 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref> | | Lipid || Phosphatidic acid ||Pii|| 2010 || 3-4 || <ref><pubmed>20826779</pubmed></ref> | ||
|- | |- | ||
| Lipid || Diacylglycerol (DAG) || 2006, 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref><ref><pubmed> 16990811</pubmed></ref> | | Lipid || Diacylglycerol (DAG) ||Daglas, DIGDA|| 2006, 2008 || 3-4 || <ref><pubmed>18685081</pubmed></ref><ref><pubmed> 16990811</pubmed></ref> | ||
|- | |- | ||
| Protein interaction || Actin || 2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref> | | Protein interaction || Actin || ||2004, 2008 || 2 || <ref><pubmed>15361876</pubmed></ref><ref><pubmed> 18512154</pubmed></ref> | ||
|- | |- | ||
| Protein interaction || PDK1-Akt interaction || 2007 || 2 || <ref><pubmed>17407381</pubmed></ref> | | Protein interaction || PDK1-Akt interaction || ||2007 || 2 || <ref><pubmed>17407381</pubmed></ref> | ||
|- | |- | ||
| Protein interaction || Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref> | | Protein interaction || Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction || || 2002 || 2 || <ref><pubmed>11872838</pubmed></ref> | ||
|- | |- | ||
| Protein interaction || Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG || 2010 || 2 || <ref><pubmed>20622991</pubmed></ref> | | Protein interaction || Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG || ||2010 || 2 || <ref><pubmed>20622991</pubmed></ref> | ||
|- | |- | ||
| Protein interaction || Cofiin-actin interaction || 2008 || 2 || <ref><pubmed>17993279</pubmed></ref> | | Protein interaction || Cofiin-actin interaction || ||2008 || 2 || <ref><pubmed>17993279</pubmed></ref> | ||
|- | |- | ||
| Protein interaction || PTEN-Myosin V interaction || 2009 || 2 || <ref><pubmed>19767745</pubmed></ref> | | Protein interaction || PTEN-Myosin V interaction || ||2009 || 2 || <ref><pubmed>19767745</pubmed></ref> | ||
|- | |- | ||
| Protease || Caspase-3 || 1998 || 1 || <ref><pubmed>9518501</pubmed></ref> | | Protease || Caspase-3 ||EGFP-DEVD-EBFP|| 1998 || 1 || <ref><pubmed>9518501</pubmed></ref> | ||
|- | |- | ||
| Protease || Caspase-8 || 2002 || 1 || <ref><pubmed>12409609</pubmed></ref> | | Protease || Caspase-8 ||CFP-c3-YFP-c6-mRFP|| 2002 || 1 || <ref><pubmed>12409609</pubmed></ref> | ||
|- | |- | ||
| Protease || Caspase-9 || 2011 || 1 || <ref><pubmed>21637712</pubmed></ref> | | Protease || Caspase-9 ||SCAT9|| 2011 || 1 || <ref><pubmed>21637712</pubmed></ref> | ||
|- | |- | ||
| Protease || Caspase-7 || 2006 || 1 || <ref><pubmed>17946841</pubmed></ref> | | Protease || Caspase-7 ||VDEVDc|| 2006 || 1 || <ref><pubmed>17946841</pubmed></ref> | ||
|- | |- | ||
| Protease || Matrix Metalloproteinase (MMP) || 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref> | | Protease || Matrix Metalloproteinase (MMP) ||YFP-MSS-CFPdisplay, MTI-MMP-FRET biosensor|| 2007, 2008 || 1 || <ref><pubmed>17187878</pubmed></ref><ref><pubmed> 18441011</pubmed></ref> | ||
|- | |- | ||
| Protease || Protease activity (Factor Xa) || 1996 || 1 || <ref><pubmed>8707050</pubmed></ref> | | Protease || Protease activity (Factor Xa) || ||1996 || 1 || <ref><pubmed>8707050</pubmed></ref> | ||
|- | |- | ||
| Protease || Calpain activity || 2000 || 1 || <ref><pubmed>10688895</pubmed></ref> | | Protease || Calpain activity ||pYSCS|| 2000 || 1 || <ref><pubmed>10688895</pubmed></ref> | ||
|- | |- | ||
| Protease || Presenilin || 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref> | | Protease || Presenilin ||GFP-PSI-RFP|| 2009 || 3-1 || <ref><pubmed>19924286</pubmed></ref> | ||
|- | |- | ||
| Other || Strain sensor || 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref> | | Other || Strain sensor ||stFRET|| 2008 || 3-1 || <ref><pubmed>18479457</pubmed></ref> | ||
|- | |- | ||
| Other || Membrane potential || 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref> | | Other || Membrane potential ||VSFP, Mermaid, ArcLight, VSFP-Butterfly|| 2001, 2008, 2012 || 3-1 || <ref><pubmed>11454036</pubmed></ref><ref><pubmed> 18622396</pubmed></ref><ref><pubmed> 22958819</pubmed></ref> | ||
|- | |- | ||
| Other || Myosin II || 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref> | | Other || Myosin II ||GSldCB|| 1998, 2006 || 3-1 || <ref><pubmed>9845076</pubmed></ref><ref><pubmed> 16939200</pubmed></ref> | ||
|- | |- | ||
| Other || HIV Rev protein || 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref> | | Other || HIV Rev protein ||YRGnC-11ad|| 2005 || 3-1 || <ref><pubmed>16013840</pubmed></ref> | ||
|- | |- | ||
| Other || Redox || 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref> | | Other || Redox ||Redoxfluor, Gaskins|| 2010, 2011 || 3-1 || <ref><pubmed>20498274</pubmed></ref><ref><pubmed> 21606117</pubmed></ref> | ||
|} | |} | ||