16,039
回編集
「セロトニン」の版間の差分
ナビゲーションに移動
検索に移動
細
編集の要約なし
細 (→セロトニン受容体) |
細編集の要約なし |
||
| 1行目: | 1行目: | ||
{{chembox | |||
| verifiedrevid = 464389317 | |||
| ImageFile = Serotonin-2D-skeletal.svg |alt=Skeletal formula of serotonin| | |||
| ImageSize = | |||
| ImageName = Skeletal formula of serotonin | |||
| ImageFile1 = Serotonin-Spartan-HF-based-on-xtal-3D-balls-web.png | |||
| ImageSize1 = | |||
| ImageName1 = Ball-and-stick model of the serotonin molecule | |||
| ImageFile2 = Serotonin-Spartan-HF-based-on-xtal-3D-sf-web.png | |||
| ImageSize2 = | |||
| ImageName2 = Space-filling model of the serotonin molecule | |||
| IUPACName = 5-Hydroxytryptamine or<br />3-(2-aminoethyl)-1''H''-indol-5-ol | |||
| OtherNames = 5-Hydroxytryptamine, 5-HT, Enteramine; Thrombocytin, 3-(β-Aminoethyl)-5-hydroxyindole, Thrombotonin | |||
| Section1 = {{Chembox Identifiers | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = 333DO1RDJY | |||
| ChEMBL_Ref = {{ebicite|correct|EBI}} | |||
| ChEMBL = 39 | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = C00780 | |||
| InChI = 1/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | |||
| InChIKey = QZAYGJVTTNCVMB-UHFFFAOYAX | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | |||
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChIKey = QZAYGJVTTNCVMB-UHFFFAOYSA-N | |||
| CASNo = 50-67-9 | |||
| CASNo_Ref = {{cascite|correct|CAS}} | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 5013 | |||
| PubChem = 5202 | |||
| IUPHAR_ligand = 5 | |||
| ChEBI_Ref = {{ebicite|correct|EBI}} | |||
| ChEBI = 28790 | |||
| SMILES = c1cc2c(cc1O)c(c[nH]2)CCN | |||
| MeSHName = Serotonin | |||
}} | |||
| Section2 = {{Chembox Properties | |||
| Formula = </sub>C<sub>10</sub>H<sub>12</sub>N<sub>2</sub>O<sub> | |||
| MolarMass = 176.215 g/mol | |||
| Appearance = White powder | |||
| Density = | |||
| pK=10.16 in water at 23.5C <ref name="pK">{{cite journal|author=Mazák, K.; Dóczy, V.; Kökösi, J.; Noszál, B. |title=Proton Speciation and Microspeciation of Serotonin and 5-Hydroxytryptophan|pmid=19353542|year=2009|volume=6|issue=4|pages=578–90|doi=10.1002/cbdv.200800087|journal=Chemistry & biodiversity}}</ref> | |||
| Solubility = slightly soluble | |||
| MeltingPt= 167.7° C | |||
| MeltingPt=121–122° C (ligroin) <ref name="MP"> Pietra, S.;Farmaco, Edizione Scientifica 1958, Vol. 13, pp. 75–9.</ref> | |||
| BoilingPt= 416 ±30.0° C (at 760 Torr) <ref name="CAPLUS"> Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994–2011 ACD/Labs)</ref> | |||
| Dipole = 2.98 [[Debye|D]] | |||
}} | |||
| Section3 = {{Chembox Structure | |||
| CrystalStruct = | |||
| SpaceGroup = | |||
| Coordination = | |||
| LattConst_a = | |||
}} | |||
| Section7 = {{Chembox Hazards | |||
| ExternalMSDS = [http://www.chemcas.com/msds/cas/msds70/50-67-9.asp External MSDS] | |||
| EUIndex = | |||
| NFPA-H = | |||
| NFPA-F = | |||
| NFPA-R = | |||
| FlashPt = | |||
| RPhrases = | |||
| SPhrases = | |||
| LD50 = 750 mg/kg (subcutaneous, rat),<ref name="rat2>{{cite journal|author=Erspamer, Vittorio|journal= Ricerca Scientifica|year=1952|volume=22|pages=694–702}}</ref> 4500 mg/kg (intraperitoneal, rat),<ref name="rat">{{cite journal|author=Tammisto, Tapani|journal= Annales Medicinae Experimentalis et Biologiea Fenniae |year=1968|volume=46|issue=3, Pt. 2|pages=382–4}}</ref> 60 mg/kg (oral, rat) | |||
}} | |||
}} | |||
英語名：serotonin、5-hydroxytryptamine 英略語：5-HT | 英語名：serotonin、5-hydroxytryptamine 英略語：5-HT | ||