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2013年10月6日 (日) 15:09時点におけるWikiSysop (トーク | 投稿記録)による版

表1．
分類 対象 年 プローブデザイン 参考文献
生体内小分子 カルシウム 1997 3-2 [1]
サイクリックGMP (cGMP) 2000, 2001, 2006 3-1 [2][3][4]
サイクリックAMP (cAMP) 2000,2004 2, 3-1 [5][6]
イノシトール3リン酸 (IP3) 2004, 2005, 2006 3-1 [7][8][9]
一酸化窒素 (NO) 2005, 2006 3-1 [10][11]
アデノシン3リン酸 (ATP) 2012 3-1 [12]
エストロゲン 2004 3-3 [13]
アンドロゲン 2006 3-3 [14]
グルココルチコイド受容体リガンド 2007 3-3 [15]
神経成長因子 2008 3-3 [16]
核内受容体 2007 3-2 [17]
O-N-アセチルグルコサミン (O-GlcNAc) 2006 3-3 [18]
ビタミンA (レチノイン酸) 2013 3-1 [19]
モリブデン酸 2013 3-1 [20]
グルタミン酸 2005 3-1 [21]
Zn2+ 2009 2 [22]
Cl- 2000 other [23]
水素イオン濃度 (pH) 2001 other [24]
グルコース 2003 3-1 [25]
マルトース 2002 3-1 [26]
リボース 2003 3-1 [27]
Kinase カルシウム/カルモジュリン依存製タンパク質キナーゼII (CaMKII) 2005, 2009, 2011, 2013 3-1 [28][29][30][31]
Kinase Src 2005, 2005, 2007 3-3 [32][33][34]
Kinase Protein kinase C (PKC) 2003, 2005 3-3, 3-1 [35][36]
Kinase Protein kinase D (PKD) 2007 3-3 [37]
Kinase Protein kinase A (PKA) 2000, 2001 3-3 [38][39]
Kinase Abl 2001 3-3 [40]
Kinase Bcr-Abl 2010 3-3 [41]
Kinase c-Raf 2005 3-1 [42]
Kinase PAK1 2009 3-1 [43]
Kinase B-raf 2006 3-1 [44]
Kinase ZAP-70 2008 3-3 [45]
Kinase Akt 2003, 2005, 2007 3-3 [46][47][48]
Kinase ERK 2006, 2007, 2008 3-1,3-3,3-3 [49][50][51]
Kinase Insulin receptor 2002 3-3 [52]
Kinase Epidermal Growth factor receptor (EGFR) 2001 3-3 [53]
Kinase Ataxia telangiectasia mutated (ATM) 2007 3-3 [54]
Kinase Aurora B kinase 2008 3-3 [55]
Kinase Cyclin B1-CDK1 2010 3-3 [56]
Kinase Myosine light chain kinase 2002 3-1 [57]
Kinase JNK 2010, 2011 3-3 [58][59]
Kinase RSK 2011 3-3 [59]
Kinase S6K 2011 3-3 [59]
Kinase Focal Adhesion Kinase (FAK) 2008, 2009 2, 3-1 [60][61]
Kinase PLK1 2008 3-3 [62]
Kinase SAP3K 2009 3-3 [63]
Kinase DAPK1 2011 3-1 [64]
Phosphatase Calcineurin 2008, 2013 3-1 [65][66]
Small GTPase Ras 2001, 2006 3-2,2 [67][68]
Small GTPase Rap 2001 3-2 [68]
Small GTPase Rac 2004 3-2 [69]
Small GTPase Rab5 2008 3-2 [70]
Small GTPase Rho 2003, 2011 3-2, 2 [71][72]
Small GTPase Cdc42 2004, 2011 3-2, 2 [73][74]
Small GTPase Ral 2004 3-3 [75]
Small GTPase TC10 2006 3-2 [76]
Signal transduction RCC1(GEF of Ran) 2008 3-1 [77]
Signal transduction CrkII phosphorylation 2001 3-1 [78]
Signal transduction N-WASP 2004 3-1 [79][80]
Signal transduction Adrenergic receptor 2003 3-1 [81]
Signal transduction Parathyroid hormone receptor 2003 3-1 [81]
Signal transduction Plasma membrane Calcium pump 2007 3-1 [82]
Acetylation Histone acetylation 2004, 2009 3-3 [83][84]
Lipid Phosphatidylinositol (3,4,5)-trisphosphate (PIP3) 2003 3-4 [85]
Lipid Phosphatidylinositol (4,5)-bisphosphate (PIP2) 2008 3-4 [86]
Lipid Phosphatidylinositol (3,4)-bisphosphate (PI(3,4)P2) 2008 3-4 [86]
Lipid Phosphatidylinositol 4-phosphate (PI4P) 2008 3-4 [86]
Lipid Phosphatidic acid 2010 3-4 [87]
Lipid Diacylglycerol (DAG) 2006, 2008 3-4 [88][89]
Protein interaction Actin 2004, 2008 2 [90][91]
Protein interaction PDK1-Akt interaction 2007 2 [92]
Protein interaction Protein tyrosine phosphatase 1B-receptor tyrosine kinases (PTP 1B-RTKs) interaction 2002 2 [93]
Protein interaction Breast cancer resistance protein/ATP-binding cassette sub-family G member) BCRP/ABCG 2010 2 [94]
Protein interaction Cofiin-actin interaction 2008 2 [95]
Protein interaction PTEN-Myosin V interaction 2009 2 [96]
Protease Caspase-3 1998 1 [97]
Protease Caspase-8 2002 1 [98]
Protease Caspase-9 2011 1 [99]
Protease Caspase-7 2006 1 [100]
Protease Matrix Metalloproteinase (MMP) 2007, 2008 1 [101][102]
Protease Protease activity (Factor Xa) 1996 1 [103]
Protease Calpain activity 2000 1 [104]
Protease Presenilin 2009 3-1 [105]
Other Strain sensor 2008 3-1 [106]
Other Membrane potential 2001, 2008, 2012 3-1 [107][108][109]
Other Myosin II 1998, 2006 3-1 [110][111]
Other HIV Rev protein 2005 3-1 [112]
Other Redox 2010, 2011 3-1 [113][114]

The numbers in the Probe Design column correspond to the section number in the “Strategies of probe design” chapter of the main text. See the webpage by Dr. Michiyuki Matsuda http://www.lif.kyoto-u.ac.jp/labs/fret/e-phogemon/unifret.htm for updated information.

  1. ↑ Miyawaki, A., Llopis, J., Heim, R., McCaffery, J.M., Adams, J.A., Ikura, M., & Tsien, R.Y. (1997).
    Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature, 388(6645), 882-7. [PubMed:9278050] [WorldCat] [DOI]
  2. ↑ Sato, M., Hida, N., Ozawa, T., & Umezawa, Y. (2000).
    Fluorescent indicators for cyclic GMP based on cyclic GMP-dependent protein kinase Ialpha and green fluorescent proteins. Analytical chemistry, 72(24), 5918-24. [PubMed:11140757] [WorldCat] [DOI]
  3. ↑ Honda, A., Adams, S.R., Sawyer, C.L., Lev-Ram, V., Tsien, R.Y., & Dostmann, W.R. (2001).
    Spatiotemporal dynamics of guanosine 3',5'-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator. Proceedings of the National Academy of Sciences of the United States of America, 98(5), 2437-42. [PubMed:11226257] [PMC] [WorldCat] [DOI]
  4. ↑ Nikolaev, V.O., Gambaryan, S., & Lohse, M.J. (2006).
    Fluorescent sensors for rapid monitoring of intracellular cGMP. Nature methods, 3(1), 23-5. [PubMed:16369548] [WorldCat] [DOI]
  5. ↑ Zaccolo, M., & Pozzan, T. (2002).
    Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Science (New York, N.Y.), 295(5560), 1711-5. [PubMed:11872839] [WorldCat] [DOI]
  6. ↑ Nikolaev, V.O., Bünemann, M., Hein, L., Hannawacker, A., & Lohse, M.J. (2004).
    Novel single chain cAMP sensors for receptor-induced signal propagation. The Journal of biological chemistry, 279(36), 37215-8. [PubMed:15231839] [WorldCat] [DOI]
  7. ↑ Tanimura, A., Nezu, A., Morita, T., Turner, R.J., & Tojyo, Y. (2004).
    Fluorescent biosensor for quantitative real-time measurements of inositol 1,4,5-trisphosphate in single living cells. The Journal of biological chemistry, 279(37), 38095-8. [PubMed:15272011] [WorldCat] [DOI]
  8. ↑ Sato, M., Ueda, Y., Shibuya, M., & Umezawa, Y. (2005).
    Locating inositol 1,4,5-trisphosphate in the nucleus and neuronal dendrites with genetically encoded fluorescent indicators. Analytical chemistry, 77(15), 4751-8. [PubMed:16053285] [WorldCat] [DOI]
  9. ↑ Matsu-ura, T., Michikawa, T., Inoue, T., Miyawaki, A., Yoshida, M., & Mikoshiba, K. (2006).
    Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cells. The Journal of cell biology, 173(5), 755-65. [PubMed:16754959] [PMC] [WorldCat] [DOI]
  10. ↑ Sato, M., Hida, N., & Umezawa, Y. (2005).
    Imaging the nanomolar range of nitric oxide with an amplifier-coupled fluorescent indicator in living cells. Proceedings of the National Academy of Sciences of the United States of America, 102(41), 14515-20. [PubMed:16176986] [PMC] [WorldCat] [DOI]
  11. ↑ Sato, M., Nakajima, T., Goto, M., & Umezawa, Y. (2006).
    Cell-based indicator to visualize picomolar dynamics of nitric oxide release from living cells. Analytical chemistry, 78(24), 8175-82. [PubMed:17165805] [WorldCat] [DOI]
  12. ↑ Imamura, H., Nhat, K.P., Togawa, H., Saito, K., Iino, R., Kato-Yamada, Y., ..., & Noji, H. (2009).
    Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators. Proceedings of the National Academy of Sciences of the United States of America, 106(37), 15651-6. [PubMed:19720993] [PMC] [WorldCat] [DOI]
  13. ↑ Awais, M., Sato, M., Sasaki, K., & Umezawa, Y. (2004).
    A genetically encoded fluorescent indicator capable of discriminating estrogen agonists from antagonists in living cells. Analytical chemistry, 76(8), 2181-6. [PubMed:15080726] [WorldCat] [DOI]
  14. ↑ Awais, M., Sato, M., Lee, X., & Umezawa, Y. (2006).
    A fluorescent indicator to visualize activities of the androgen receptor ligands in single living cells. Angewandte Chemie (International ed. in English), 45(17), 2707-12. [PubMed:16555356] [WorldCat] [DOI]
  15. ↑ Awais, M., Sato, M., & Umezawa, Y. (2007).
    Optical probes to identify the glucocorticoid receptor ligands in living cells. Steroids, 72(14), 949-54. [PubMed:17897691] [WorldCat] [DOI]
  16. ↑ Nakajima, T., Sato, M., Akaza, N., & Umezawa, Y. (2008).
    Cell-based fluorescent indicator to visualize brain-derived neurotrophic factor secreted from living neurons. ACS chemical biology, 3(6), 352-8. [PubMed:18510313] [WorldCat] [DOI]
  17. ↑ Awais, M., Sato, M., & Umezawa, Y. (2007).
    Imaging of selective nuclear receptor modulator-induced conformational changes in the nuclear receptor to allow interaction with coactivator and corepressor proteins in living cells. Chembiochem : a European journal of chemical biology, 8(7), 737-43. [PubMed:17387660] [WorldCat] [DOI]
  18. ↑ Carrillo, L.D., Krishnamoorthy, L., & Mahal, L.K. (2006).
    A cellular FRET-based sensor for beta-O-GlcNAc, a dynamic carbohydrate modification involved in signaling. Journal of the American Chemical Society, 128(46), 14768-9. [PubMed:17105262] [WorldCat] [DOI]
  19. ↑ Shimozono, S., Iimura, T., Kitaguchi, T., Higashijima, S., & Miyawaki, A. (2013).
    Visualization of an endogenous retinoic acid gradient across embryonic development. Nature, 496(7445), 363-6. [PubMed:23563268] [WorldCat] [DOI]
  20. ↑ Nakanishi, Y., Iida, S., Ueoka-Nakanishi, H., Niimi, T., Tomioka, R., & Maeshima, M. (2013).
    Exploring dynamics of molybdate in living animal cells by a genetically encoded FRET nanosensor. PloS one, 8(3), e58175. [PubMed:23472155] [PMC] [WorldCat] [DOI]
  21. ↑ Okumoto, S., Looger, L.L., Micheva, K.D., Reimer, R.J., Smith, S.J., & Frommer, W.B. (2005).
    Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors. Proceedings of the National Academy of Sciences of the United States of America, 102(24), 8740-5. [PubMed:15939876] [PMC] [WorldCat] [DOI]
  22. ↑ Vinkenborg, J.L., Nicolson, T.J., Bellomo, E.A., Koay, M.S., Rutter, G.A., & Merkx, M. (2009).
    Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis. Nature methods, 6(10), 737-40. [PubMed:19718032] [PMC] [WorldCat] [DOI]
  23. ↑ Kuner, T., & Augustine, G.J. (2000).
    A genetically encoded ratiometric indicator for chloride: capturing chloride transients in cultured hippocampal neurons. Neuron, 27(3), 447-59. [PubMed:11055428] [WorldCat] [DOI]
  24. ↑ Awaji, T., Hirasawa, A., Shirakawa, H., Tsujimoto, G., & Miyazaki, S. (2001).
    Novel green fluorescent protein-based ratiometric indicators for monitoring pH in defined intracellular microdomains. Biochemical and biophysical research communications, 289(2), 457-62. [PubMed:11716495] [WorldCat] [DOI]
  25. ↑ Fehr, M., Lalonde, S., Lager, I., Wolff, M.W., & Frommer, W.B. (2003).
    In vivo imaging of the dynamics of glucose uptake in the cytosol of COS-7 cells by fluorescent nanosensors. The Journal of biological chemistry, 278(21), 19127-33. [PubMed:12649277] [WorldCat] [DOI]
  26. ↑ Fehr, M., Frommer, W.B., & Lalonde, S. (2002).
    Visualization of maltose uptake in living yeast cells by fluorescent nanosensors. Proceedings of the National Academy of Sciences of the United States of America, 99(15), 9846-51. [PubMed:12097642] [PMC] [WorldCat] [DOI]
  27. ↑ Lager, I., Fehr, M., Frommer, W.B., & Lalonde, S. (2003).
    Development of a fluorescent nanosensor for ribose. FEBS letters, 553(1-2), 85-9. [PubMed:14550551] [WorldCat] [DOI]
  28. ↑ Takao, K., Okamoto, K., Nakagawa, T., Neve, R.L., Nagai, T., Miyawaki, A., ..., & Hayashi, Y. (2005).
    Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(12), 3107-12. [PubMed:15788767] [PMC] [WorldCat] [DOI]
  29. ↑ Lee, S.J., Escobedo-Lozoya, Y., Szatmari, E.M., & Yasuda, R. (2009).
    Activation of CaMKII in single dendritic spines during long-term potentiation. Nature, 458(7236), 299-304. [PubMed:19295602] [PMC] [WorldCat] [DOI]
  30. ↑ Fujii, H., Inoue, M., Okuno, H., Sano, Y., Takemoto-Kimura, S., Kitamura, K., ..., & Bito, H. (2013).
    Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIα and calcineurin. Cell reports, 3(4), 978-87. [PubMed:23602566] [WorldCat] [DOI]
  31. ↑ Piljić, A., de Diego, I., Wilmanns, M., & Schultz, C. (2011).
    Rapid development of genetically encoded FRET reporters. ACS chemical biology, 6(7), 685-91. [PubMed:21506563] [WorldCat] [DOI]
  32. ↑ Ting, A.Y., Kain, K.H., Klemke, R.L., & Tsien, R.Y. (2001).
    Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells. Proceedings of the National Academy of Sciences of the United States of America, 98(26), 15003-8. [PubMed:11752449] [PMC] [WorldCat] [DOI]
  33. ↑ Wang, Y., Botvinick, E.L., Zhao, Y., Berns, M.W., Usami, S., Tsien, R.Y., & Chien, S. (2005).
    Visualizing the mechanical activation of Src. Nature, 434(7036), 1040-5. [PubMed:15846350] [WorldCat] [DOI]
  34. ↑ Hitosugi, T., Sasaki, K., Sato, M., Suzuki, Y., & Umezawa, Y. (2007).
    Epidermal growth factor directs sex-specific steroid signaling through Src activation. The Journal of biological chemistry, 282(14), 10697-706. [PubMed:17284441] [WorldCat] [DOI]
  35. ↑ Violin, J.D., Zhang, J., Tsien, R.Y., & Newton, A.C. (2003).
    A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. The Journal of cell biology, 161(5), 899-909. [PubMed:12782683] [PMC] [WorldCat] [DOI]
  36. ↑ Braun, D.C., Garfield, S.H., & Blumberg, P.M. (2005).
    Analysis by fluorescence resonance energy transfer of the interaction between ligands and protein kinase Cdelta in the intact cell. The Journal of biological chemistry, 280(9), 8164-71. [PubMed:15611119] [WorldCat] [DOI]
  37. ↑ Kunkel, M.T., Toker, A., Tsien, R.Y., & Newton, A.C. (2007).
    Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter. The Journal of biological chemistry, 282(9), 6733-42. [PubMed:17189263] [PMC] [WorldCat] [DOI]
  38. ↑ Nagai, Y., Miyazaki, M., Aoki, R., Zama, T., Inouye, S., Hirose, K., ..., & Hagiwara, M. (2000).
    A fluorescent indicator for visualizing cAMP-induced phosphorylation in vivo. Nature biotechnology, 18(3), 313-6. [PubMed:10700148] [WorldCat] [DOI]
  39. ↑ Zhang, J., Ma, Y., Taylor, S.S., & Tsien, R.Y. (2001).
    Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proceedings of the National Academy of Sciences of the United States of America, 98(26), 14997-5002. [PubMed:11752448] [PMC] [WorldCat] [DOI]
  40. ↑ Ting, A.Y., Kain, K.H., Klemke, R.L., & Tsien, R.Y. (2001).
    Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells. Proceedings of the National Academy of Sciences of the United States of America, 98(26), 15003-8. [PubMed:11752449] [PMC] [WorldCat] [DOI]
  41. ↑ Tunceroglu, A., Matsuda, M., & Birge, R.B. (2010).
    Real-time fluorescent resonance energy transfer analysis to monitor drug resistance in chronic myelogenous leukemia. Molecular cancer therapeutics, 9(11), 3065-73. [PubMed:20817824] [PMC] [WorldCat] [DOI]
  42. ↑ Terai, K., & Matsuda, M. (2005).
    Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase. EMBO reports, 6(3), 251-5. [PubMed:15711535] [PMC] [WorldCat] [DOI]
  43. ↑ Parrini, M.C., Camonis, J., Matsuda, M., & de Gunzburg, J. (2009).
    Dissecting activation of the PAK1 kinase at protrusions in living cells. The Journal of biological chemistry, 284(36), 24133-43. [PubMed:19574218] [PMC] [WorldCat] [DOI]
  44. ↑ Terai, K., & Matsuda, M. (2006).
    The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf. The EMBO journal, 25(15), 3556-64. [PubMed:16858395] [PMC] [WorldCat] [DOI]
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    A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse. PloS one, 3(1), e1521. [PubMed:18231606] [PMC] [WorldCat] [DOI]
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    Fluorescent indicators for Akt/protein kinase B and dynamics of Akt activity visualized in living cells. The Journal of biological chemistry, 278(33), 30945-51. [PubMed:12773546] [WorldCat] [DOI]
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    Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter. The Journal of biological chemistry, 280(7), 5581-7. [PubMed:15583002] [PMC] [WorldCat] [DOI]
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    Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo. PLoS biology, 5(4), e95. [PubMed:17407381] [PMC] [WorldCat] [DOI]
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    Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes. The Journal of biological chemistry, 281(13), 8917-26. [PubMed:16418172] [WorldCat] [DOI]
  50. ↑ Sato, M., Kawai, Y., & Umezawa, Y. (2007).
    Genetically encoded fluorescent indicators to visualize protein phosphorylation by extracellular signal-regulated kinase in single living cells. Analytical chemistry, 79(6), 2570-5. [PubMed:17261026] [WorldCat] [DOI]
  51. ↑ Harvey, C.D., Ehrhardt, A.G., Cellurale, C., Zhong, H., Yasuda, R., Davis, R.J., & Svoboda, K. (2008).
    A genetically encoded fluorescent sensor of ERK activity. Proceedings of the National Academy of Sciences of the United States of America, 105(49), 19264-9. [PubMed:19033456] [PMC] [WorldCat] [DOI]
  52. ↑ Sato, M., Ozawa, T., Inukai, K., Asano, T., & Umezawa, Y. (2002).
    Fluorescent indicators for imaging protein phosphorylation in single living cells. Nature biotechnology, 20(3), 287-94. [PubMed:11875431] [WorldCat] [DOI]
  53. ↑ Ting, A.Y., Kain, K.H., Klemke, R.L., & Tsien, R.Y. (2001).
    Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells. Proceedings of the National Academy of Sciences of the United States of America, 98(26), 15003-8. [PubMed:11752449] [PMC] [WorldCat] [DOI]
  54. ↑ Johnson, S.A., You, Z., & Hunter, T. (2007).
    Monitoring ATM kinase activity in living cells. DNA repair, 6(9), 1277-84. [PubMed:17428747] [WorldCat] [DOI]
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    Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature, 453(7198), 1132-6. [PubMed:18463638] [PMC] [WorldCat] [DOI]
  56. ↑ Gavet, O., & Pines, J. (2010).
    Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis. Developmental cell, 18(4), 533-43. [PubMed:20412769] [PMC] [WorldCat] [DOI]
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    A fluorescent resonant energy transfer-based biosensor reveals transient and regional myosin light chain kinase activation in lamella and cleavage furrows. The Journal of cell biology, 156(3), 543-53. [PubMed:11815633] [PMC] [WorldCat] [DOI]
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    Visualization of JNK activity dynamics with a genetically encoded fluorescent biosensor. Proceedings of the National Academy of Sciences of the United States of America, 107(12), 5459-64. [PubMed:20212108] [PMC] [WorldCat] [DOI]
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    Development of an optimized backbone of FRET biosensors for kinases and GTPases. Molecular biology of the cell, 22(23), 4647-56. [PubMed:21976697] [PMC] [WorldCat] [DOI]
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    Spatial and temporal regulation of focal adhesion kinase activity in living cells. Molecular and cellular biology, 28(1), 201-14. [PubMed:17967873] [PMC] [WorldCat] [DOI]
  61. ↑ Papusheva, E., Mello de Queiroz, F., Dalous, J., Han, Y., Esposito, A., Jares-Erijmanxa, E.A., ..., & Bunt, G. (2009).
    Dynamic conformational changes in the FERM domain of FAK are involved in focal-adhesion behavior during cell spreading and motility. Journal of cell science, 122(Pt 5), 656-66. [PubMed:19208768] [WorldCat] [DOI]
  62. ↑ Macůrek, L., Lindqvist, A., Lim, D., Lampson, M.A., Klompmaker, R., Freire, R., ..., & Medema, R.H. (2008).
    Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery. Nature, 455(7209), 119-23. [PubMed:18615013] [WorldCat] [DOI]
  63. ↑ Tomida, T., Takekawa, M., O'Grady, P., & Saito, H. (2009).
    Stimulus-specific distinctions in spatial and temporal dynamics of stress-activated protein kinase kinase kinases revealed by a fluorescence resonance energy transfer biosensor. Molecular and cellular biology, 29(22), 6117-27. [PubMed:19737916] [PMC] [WorldCat] [DOI]
  64. ↑ Piljić, A., de Diego, I., Wilmanns, M., & Schultz, C. (2011).
    Rapid development of genetically encoded FRET reporters. ACS chemical biology, 6(7), 685-91. [PubMed:21506563] [WorldCat] [DOI]
  65. ↑ Fujii, H., Inoue, M., Okuno, H., Sano, Y., Takemoto-Kimura, S., Kitamura, K., ..., & Bito, H. (2013).
    Nonlinear decoding and asymmetric representation of neuronal input information by CaMKIIα and calcineurin. Cell reports, 3(4), 978-87. [PubMed:23602566] [WorldCat] [DOI]
  66. ↑ Newman, R.H., & Zhang, J. (2008).
    Visualization of phosphatase activity in living cells with a FRET-based calcineurin activity sensor. Molecular bioSystems, 4(6), 496-501. [PubMed:18493642] [WorldCat] [DOI]
  67. ↑ Yasuda, R., Harvey, C.D., Zhong, H., Sobczyk, A., van Aelst, L., & Svoboda, K. (2006).
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