「GSK-3β」の版間の差分

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GSK-3β (ソースを閲覧)

2012年10月10日 (水) 15:35時点における版

2,812 バイト除去 、 2012年10月10日 (水)
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Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation.
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An alternatively spliced form of glycogen synthase kinase-3beta is targeted to growing neurites and growth cones.
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Glycogen synthase kinase-3: functions in oncogenesis and development.
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'''4. Dajani R'''
Crystal structure of glycogen synthase kinase 3 beta: strustural basis for phosphate-primed substrate specificity and autoinhibition.
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'''5.&nbsp;Hur EM, Zhou FQ'''
GSK3 signalling in neural development.<br>''Nat Rev Neurosci.:&nbsp;2010, ''11 (8); 539-51&nbsp;[PubMed&nbsp;20648061]&nbsp;
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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.<br>''Cell:'' 1993,&nbsp;75 (7);&nbsp;1417-30&nbsp;[PubMed&nbsp;7916661&nbsp;]
'''7. Price MA, Kalderon D'''
Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.
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'''8.&nbsp;Smelkinson MG, Kalderon D<br>'''Processing of the Drosophila hedgehog signaling effector Ci-155 to the repressor Ci-75 is mediated by direct binding to the SCF component Slimb.<br>''Curr Biol.:'' 2006,&nbsp;16 (1):110-6 [PubMed 16386907&nbsp;]
'''9. Chen Y, Yue S, Xie L, Pu XH, Jin T, Cheng SY'''
Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium.<br>''J Biol Chem.: ''2011,&nbsp;286 (15):13502-11 [PubMed&nbsp;21317289]<br>
'''10. Fukata Y, Itoh TJ, Kimura T, Ménager C, Nishimura T, Shiromizu T, Watanabe H, Inagaki N, Iwamatsu A, Hotani H, Kaibuchi K'''
CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.<br>''Nat Cell Biol.: ''2002, 4 (8); 583-91[PubMed 12134159 ]
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GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.<br>''Cell.: ''2005, 120 (1):137-49.<br>




（執筆者：河野利恵、太田訓正　担当編集委員：大隅典子)
（執筆者：河野利恵、太田訓正　担当編集委員：大隅典子)
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